Editor-in-Chief Emeritus Pick of Papers
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For each issue of Radiotherapy and Oncology, the Editor-in-Chief Emeritus Jens Overgaard, picks his favourite papers.
- A patient with a cutaneous lymphoma was treated on the same day for 2 distinct tumors using a 15 Gy single electron dose given in a dose rate of 0.08 Gy/second versus 166 Gy/second. Comparing the two treatments, there was no difference for acute reactions, late effects at 2 years and tumor control.
- Intensity Modulated Radiation Therapy (IMRT), Volumetric Modulated Arctherapy (VMAT) or other highly conformal techniques (e.g. proton therapy) are techniques that allow precise targeting of the volumes to be irradiated while protecting healthy tissue. In 2018, it is the standard method of irradiation of head and neck cancers [1–5]. Because of their precision, these techniques require that each target volume be strictly and rigorously defined. The delineation and selection of these volumes is complex and requires a solid learning curve.
- Perineural invasion (PNI) is a well-recognized characteristics in head and neck cancers. It has been associated with poor prognosis, i.e. increased loco-regional recurrence and decreased survival [1–6]. PNI can present from either cutaneous, mucosal, or salivary gland head and neck malignancies . Adenoid cystic carcinoma (ACC) and squamous-cell carcinomas (SCC) are the most frequent neoplasms to exhibit this behavior. PNI is a clinicopathological entity generally defined as tumor-cell invasion in, around, and through the nerves [8,9].
- Stereotactic body radiotherapy (SBRT) is an emerging non-invasive treatment in the management of ventricular tachycardia (VT). We report here an intensive care patient suffering from an electrical storm due to incessant VT, unresponsive to catheter ablation and anti-arrhythmic drugs, showing an immediate and durable response to electrophysiology-guided cardiac SBRT.