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Response to Gargi S Sarode, Sachin C Sarode, and Rahul Anand’s Letter to the Editor of Radiotherapy and Oncology regarding the paper titled “Impact on xerostomia for nasopharyngeal carcinoma patients treated with superficial parotid lobe-sparing intensity-modulated radiation therapy (SPLS-IMRT): A prospective phase II randomized controlled study.” by Huang et al.

  • Huageng Huang
    Affiliations
    Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou 510060, China
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  • Jingjing Miao
    Affiliations
    Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou 510060, China
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  • Chong Zhao
    Correspondence
    Corresponding authors at: Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China.
    Affiliations
    Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou 510060, China
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  • Lin Wang
    Correspondence
    Corresponding authors at: Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China.
    Affiliations
    Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou 510060, China
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Published:November 02, 2022DOI:https://doi.org/10.1016/j.radonc.2022.10.022
      We are very grateful for these great comments made by Prof. Sachin C Sarode and his teams [
      • Sarode G.S.
      • Sarode S.C.
      • Anand R.
      Letter to the Editor of Radiotherapy and Oncology regarding the paper titled “Impact on xerostomia for nasopharyngeal carcinoma patients treated with superficial parotid lobe-sparing intensity-modulated radiation therapy (SPLS-IMRT): A prospective phase II randomized controlled study.” by Huang et al..
      ] about our recent article [
      • Huang H.
      • Miao J.
      • Xiao X.
      • et al.
      Impact on xerostomia for nasopharyngeal carcinoma patients treated with superficial parotid lobe-sparing intensity-modulated radiation therapy (SPLS-IMRT): A prospective phase II randomized controlled study.
      ]. We agree that chronic betel quid (BQ) and alcohol consumption habits and Type 2 diabetes will have a negative influence on patients’ salivary functions and probably aggravate the severity of xerostomia, just as previous studies reported [
      • Celik N.
      • Wei F.C.
      • Chang Y.M.
      • et al.
      Squamous cell carcinoma of the oral mucosa after release of submucous fibrosis and bilateral small radial forearm flap reconstruction.
      ,
      • Inenaga K.
      • Ono K.
      • Hitomi S.
      • et al.
      Thirst sensation and oral dryness following alcohol intake.
      ,
      • Rahiotis C.
      • Petraki V.
      • Mitrou P.
      Changes in saliva characteristics and carious status related to metabolic control in patients with type 2 diabetes mellitus.
      ]. Hereby, we want to provide more information on these aspects.
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      References

        • Sarode G.S.
        • Sarode S.C.
        • Anand R.
        Letter to the Editor of Radiotherapy and Oncology regarding the paper titled “Impact on xerostomia for nasopharyngeal carcinoma patients treated with superficial parotid lobe-sparing intensity-modulated radiation therapy (SPLS-IMRT): A prospective phase II randomized controlled study.” by Huang et al..
        Radiother Oncol. 2022; (in press)
        • Huang H.
        • Miao J.
        • Xiao X.
        • et al.
        Impact on xerostomia for nasopharyngeal carcinoma patients treated with superficial parotid lobe-sparing intensity-modulated radiation therapy (SPLS-IMRT): A prospective phase II randomized controlled study.
        Radiotherapy Oncol. 2022; 175: 1-9
        • Celik N.
        • Wei F.C.
        • Chang Y.M.
        • et al.
        Squamous cell carcinoma of the oral mucosa after release of submucous fibrosis and bilateral small radial forearm flap reconstruction.
        Plastic Reconstruct Surgery. 2002; 110: 34-38
        • Inenaga K.
        • Ono K.
        • Hitomi S.
        • et al.
        Thirst sensation and oral dryness following alcohol intake.
        Jpn Dent Sci Rev. 2017; 53: 78-85
        • Rahiotis C.
        • Petraki V.
        • Mitrou P.
        Changes in saliva characteristics and carious status related to metabolic control in patients with type 2 diabetes mellitus.
        J Dent. 2021; 108: 103629

      Linked Article