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High dose rate brachytherapy for anal cancer: A review of a systematic review

      We read with interest the systematic review by Ali et al. [
      • Ali Z.S.
      • Solomon E.
      • Mann P.
      • Wong S.
      • Chan K.K.W.
      • Taggar A.S.
      High dose rate brachytherapy in the management of anal cancer: a review.
      ]. They reported on 10 studies that included patients with anal cancer treated with high dose rate brachytherapy. They narratively presented the results of each study, as well as computed a weighted mean average of local control and survival. Given the limited data available to date (only 321 patients assessed across the 10 studies), we applaud the authors for this important undertaking. We do, however, have some reservations with respect to the methodology that should warrant cautious interpretation of the results beyond the studies being predominantly retrospective and reported over 30 years, as discussed by the authors.
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      References

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        • Solomon E.
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        High dose rate brachytherapy in the management of anal cancer: a review.
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