Advertisement

Letter to the editor of radiotherapy and oncology regarding of the article “Dosimetric parameters related to occurrence of distant metastases and regional nodal relapse after SBRT for early-stage non-small cell lung cancer” by Lalonde et al.

  • Kaixuan Yang
    Affiliations
    Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China
    Search for articles by this author
  • Chuntang Sun
    Correspondence
    Corresponding authors at: West China Second University Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, Sichuan 610041, China (C. Sun). West China Second University Hospital, Sichuan University, No. 1416, Section 1, Chenglong Road, Chengdu, Sichuan 610066, China (R. Yin).
    Affiliations
    Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China
    Search for articles by this author
  • Rutie Yin
    Correspondence
    Corresponding authors at: West China Second University Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu, Sichuan 610041, China (C. Sun). West China Second University Hospital, Sichuan University, No. 1416, Section 1, Chenglong Road, Chengdu, Sichuan 610066, China (R. Yin).
    Affiliations
    Department of Gynecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China
    Search for articles by this author
      The goal of this letter is not to underestimate the work done by Lalonde and colleagues [
      • Lalonde R.
      • Abdelhakiem M.
      • Keller A.
      • Huq M.S.
      Dosimetric parameters related to occurrence of distant metastases and regional nodal relapse after SBRT for early-stage non-small cell lung cancer.
      ], “Dosimetric parameters related to occurrence of distant metastases and regional nodal relapse after SBRT for early-stage non-small cell lung cancer” published on Radiotherapy and Oncology in 2022. Instead, this letter intends to draw attention to certain incorrect conclusions concerning four-dimensional CT (4D-CT), which appear to be based on different respiratory motion management strategies in lung cancer radiotherapy [
      • Lalonde R.
      • Abdelhakiem M.
      • Keller A.
      • Huq M.S.
      Dosimetric parameters related to occurrence of distant metastases and regional nodal relapse after SBRT for early-stage non-small cell lung cancer.
      ,
      • Diamant A.
      • Chatterjee A.
      • Faria S.
      • Naqa I.E.
      • Bahig H.
      • Filion E.
      • et al.
      Can dose outside the PTV influence the risk of distant metastases in stage I lung cancer patients treated with stereotactic body radiotherapy (SBRT)?.
      ]. In this study, the authors conducted a retrospective study involving 304 patients with early-stage NSCLC in US. Their data did not replicate the correlation between lower dose in the periphery of lung SBRT targets and increased rate of distant metastases shown in Diamant et al. published on Radiotherapy and Oncology in 2018 [
      • Diamant A.
      • Chatterjee A.
      • Faria S.
      • Naqa I.E.
      • Bahig H.
      • Filion E.
      • et al.
      Can dose outside the PTV influence the risk of distant metastases in stage I lung cancer patients treated with stereotactic body radiotherapy (SBRT)?.
      ]. The results are impressive. However, we have to communicate with the authors regarding several concerns.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Radiotherapy and Oncology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Lalonde R.
        • Abdelhakiem M.
        • Keller A.
        • Huq M.S.
        Dosimetric parameters related to occurrence of distant metastases and regional nodal relapse after SBRT for early-stage non-small cell lung cancer.
        Radiother Oncol. 2022; 169: 90-95
        • Diamant A.
        • Chatterjee A.
        • Faria S.
        • Naqa I.E.
        • Bahig H.
        • Filion E.
        • et al.
        Can dose outside the PTV influence the risk of distant metastases in stage I lung cancer patients treated with stereotactic body radiotherapy (SBRT)?.
        Radiother Oncol. 2018; 128: 513-519
        • Clements N.
        • Kron T.
        • Franich R.
        • Dunn L.
        • Roxby P.
        • Aarons Y.
        • et al.
        The effect of irregular breathing patterns on internal target volumes in four-dimensional CT and cone-beam CT images in the context of stereotactic lung radiotherapy.
        Med Phys. 2013; 40: 021904
        • Britton K.R.
        • Starkschall G.
        • Tucker S.L.
        • Pan T.
        • Nelson C.
        • Chang J.Y.
        • et al.
        Assessment of gross tumor volume regression and motion changes during radiotherapy for non-small-cell lung cancer as measured by four-dimensional computed tomography.
        Int J Radiat Oncol Biol Phys. 2007; 68: 1036-1046
        • James S.S.
        • Mishra P.
        • Hacker F.
        • Berbeco R.I.
        • Lewis J.H.
        Quantifying ITV instabilities arising from 4DCT: a simulation study using patient data.
        Phys Med Biol. 2012; 57: L1-L7
        • Wolthaus J.W.H.
        • Sonke J.-J.
        • van Herk M.
        • Belderbos J.S.A.
        • Rossi M.M.G.
        • Lebesque J.V.
        • et al.
        Comparison of different strategies to use four-dimensional computed tomography in treatment planning for lung cancer patients.
        Int J Radiat Oncol Biol Phys. 2008; 70: 1229-1238
        • Rodriguez L.L.
        • Kotecha R.
        • Tom M.C.
        • Chuong M.D.
        • Contreras J.A.
        • Romaguera T.
        • et al.
        CT-guided versus MR-guided radiotherapy: Impact on gastrointestinal sparing in adrenal stereotactic body radiotherapy.
        Radiother Oncol. 2022; 166: 101-109
        • Scotti V.
        • Marrazzo L.
        • Saieva C.
        • Agresti B.
        • Meattini I.
        • Desideri I.
        • et al.
        Impact of a breathing-control system on target margins and normal-tissue sparing in the treatment of lung cancer: experience at the radiotherapy unit of Florence University.
        Radiol Med. 2014; 119: 13-19
        • Gong G.
        • Wang R.
        • Guo Y.
        • Zhai D.
        • Liu T.
        • Lu J.
        • et al.
        Reduced lung dose during radiotherapy for thoracic esophageal carcinoma: VMAT combined with active breathing control for moderate DIBH.
        Radiat Oncol. 2013; 8: 291
        • van Loon J.
        • Siedschlag C.
        • Stroom J.
        • Blauwgeers H.
        • van Suylen R.-J.
        • Knegjens J.
        • et al.
        Microscopic disease extension in three dimensions for non-small-cell lung cancer: development of a prediction model using pathology-validated positron emission tomography and computed tomography features.
        Int J Radiat Oncol Biol Phys. 2012; 82: 448-456

      Linked Article