- •Pelvic (active) bone marrow (BM) sparing radiotherapy plans reduced pelvic (active) BM irradiation dose.
- •Pooled analysis found that pelvic BM-sparing radiotherapy decreased the incidence of G2+ and G3+ hematological toxicity (OR 0.31/0.42, P < 0.0001).
- •No significant differences in gastrointestinal and urological toxicity were observed between pelvic BM-sparing and non-sparing radiotherapy.
- •Pelvic active BM-sparing radiotherapy also decreased hematologic toxicity (OR 0.42/0.21, P < 0.01).
- •Clinical benefits of pelvic active BM-sparing radiotherapy over pelvic BM-sparing remains to be further investigated.
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