Abstract
The past decade has provided many technological advances in radiotherapy. The European
Institute of Radiotherapy (EIR) was established by the European Society of Therapeutic
Radiology and Oncology (ESTRO) to provide current consensus statement with evidence-based
and pragmatic guidelines on topics of practical relevance for radiation oncology.
This report focuses primarily on 3D CT-based in-room image guidance (3DCT-IGRT) systems.
It will provide an overview and current standing of 3DCT-IGRT systems addressing the
rationale, objectives, principles, applications, and process pathways, both clinical
and technical for treatment delivery and quality assurance. These are reviewed for
four categories of solutions; kV CT and kV CBCT (cone-beam CT) as well as MV CT and
MV CBCT. It will also provide a framework and checklist to consider the capability
and functionality of these systems as well as the resources needed for implementation.
Two different but typical clinical cases (tonsillar and prostate cancer) using 3DCT-IGRT
are illustrated with workflow processes via feedback questionnaires from several large
clinical centres currently utilizing these systems. The feedback from these clinical
centres demonstrates a wide variability based on local practices. This report whilst
comprehensive is not exhaustive as this area of development remains a very active
field for research and development. However, it should serve as a practical guide
and framework for all professional groups within the field, focussed on clinicians,
physicists and radiation therapy technologists interested in IGRT.
Keywords
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Article info
Publication history
Published online: February 15, 2010
Accepted:
January 16,
2010
Received in revised form:
January 8,
2010
Received:
October 31,
2009
Identification
Copyright
© 2010 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
