Advertisement
Educational review| Volume 84, ISSUE 3, P335-347, September 2007

Download started.

Ok

Anatomical bases for the radiological delineation of lymph node areas. Upper limbs, chest and abdomen

  • Benoit Lengelé
    Affiliations
    Department of Experimental Morphology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Bruxelles, Belgium
    Search for articles by this author
  • Catherine Nyssen-behets
    Affiliations
    Department of Experimental Morphology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Bruxelles, Belgium
    Search for articles by this author
  • Pierre Scalliet
    Correspondence
    Corresponding author. Pierre Scalliet, Department of Radiation Oncology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, 10, Avenue Hippocrate, B-1200 Bruxelles, Belgium.
    Affiliations
    Department of Radiation Oncology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain, Bruxelles, Belgium
    Search for articles by this author

      Abstract

      Cancer spreads locally through direct infiltration into soft tissues, or at distance by invading vascular structures, then migrating through the lymphatic or blood flow. Although cancer cells carried in the blood can end in virtually any corner of the body, lymphatic migration is usually stepwise, through successive nodal stops, which can temporarily delay further progression. In radiotherapy, irradiation of lymphatic paths relevant to the localisation of the primary has been common practice for decades. Similarly, excision of cancer is often completed by lymphatic dissection.
      Both in radiotherapy and in surgery, advanced knowledge of the lymphatic pathways relevant to any tumour location is an important information for treatment preparation and execution. This second part describes the lymphatics of the upper limb, of the thorax and of the upper abdomen. Providing anatomical bases for the radiological delineation of lymph nodes areas in the axilla, in the chest and in the abdomen, it also offers a simplified classification for labeling the mediastinal and intra-abdominal nodal levels, grouped in each location inside three major functional areas (called I, II and III) which are all divided into three sublevels (named a, b or c).

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Radiotherapy and Oncology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Berg J.W.
        The significance of axillary node levels in the study of breast cancer.
        Cancer. 1955; 63: 776-778
        • Caplan I.
        Anatomical review of the lymph nodes of the mediastinum.
        Surg Radiol Anat. 1990; 12: 9-18
        • Gregoire V.
        • Coche E.
        • Cosnard G.
        • et al.
        Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy. Proposal for standardizing terminology and procedure based on the surgical experience.
        Radiother Oncol. 2000; 56: 135-150
        • Kajitani T.
        Japanese research society for the study of gastric cancer. The general rules for gastric cancer study in surgery and pathology.
        Jpn J Surg. 1981; 11: 127-145
        • Kirikuta I.C.
        Target volume selection and delineation in breast cancer conformal radiotherapy.
        in: Gregoire V. Scalliet P. Ang K.K. Clinical target volume in conformal and intensity modulated radiotherapy. A clinical guide to cancer treatment. Springer Verlag, Berlin, Heidelberg, New York2004: 121-143
        • Korst R.J.
        • Rush V.W.
        • Venkatraman E.
        • et al.
        Proposed revision of the staging classification for esophageal cancer.
        J Thoracic Cardiovasc Surg. 1998; 3: 660-670
      1. Kubik S. Efferente LymphgefäBe und die regionale Lymphnoten der Brustdrüse. In: Földi, M, Kubik, S, editor. Lehrbuch der Lymphologie. Ath ed. Stuttgart, Jean, Lübeck, Ulm: Fischer; 1999. p. 137–52.

        • Lengele B.G.
        The lymphatic system.
        in: Gregoire V. Scalliet P. Ang K.K. Clinical target volume in conformal and intensity modulated radiotherapy. A clinical guide to cancer treatment. Springer Verlag, Berlin, Heidelberg, New York2004: 1-36
        • Lengele B.G.
        • Hamoir M.
        • Scalliet P.
        • Gregoire V.
        Anatomical bases for the radiological delineation of lymph node areas. Major collecting trunks, head and neck.
        Radiother Oncol. 2007; https://doi.org/10.1016/j.radonc.2007.02.009
        • Moutain C.F.
        • Dressler C.M.
        Regional lymph node classification for lung cancer staging.
        Chest. 1997; 111: 1718-1723
        • Plentl A.A.
        • Friedman E.A.
        Lymphatic system of the female genitalia. The morphologic basis of oncologic diagnosis and therapy.
        Saunders, Philadelphia1971
        • Poirier P.
        • Cuneo B.
        • Delamere G.
        The lymphatics.
        Archibald Constable & Co. Ltd., Westminster1903
        • Riquet M.
        • Pimpec-barthes L.E.
        • Hidden G.
        Lymphatic drainage of the pericardium to the mediastinal lymph nodes.
        Surg Radiol Anat. 2001; 23: 317-319
        • Rouviere H.
        • Tobias M.J.
        Anatomy of the human lymphatic system.
        Edwards, Ann Arbor1938
      2. Sappey PC. Des vaisseaux lymphatiques. In: Sappey PC, editor. Traité d’anatomie descriptive, vol. 2. Paris: Delahaye A, Lecrosnier E; 1888. p. 731–842.

        • Senan S.
        • Van Sörnsen De Koste j.
        • Samson M.
        • et al.
        Evaluation of a target contouring protocol for 3D conformal radiotherapy in non-small-cell lung cancer.
        Radiother Oncol. 1999; 53: 247-255
      3. Testut L. Des lymphatiques. In: Testut L, editor. Traité d’anatomie humaine, vol. 2. Paris: Doin; 1893. p. 267–308.

        • Valentini V.
        • Dinapoli N.
        • Nori S.
        • et al.
        An application of visible human database in radiotherapy: tutorial for image guided external radiotherapy (TIGER).
        Radiother Oncol. 2004; 70: 165-169
        • Warwick R.
        • Williams P.
        Topography of the lymph nodes and vessels.
        in: Gray’s anatomy. 35th ed. Longman, Edinburgh1973: 727-744
        • Whitmore I.
        Lymphoid system.
        in: Federative Committee on Anatomical Terminology – terminologica anatomica. Thieme Verlag, Stuttgart1998: 100-103