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Editorial Board
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ii
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Contents
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vii-viii
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| Systematic review |
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Radiation-induced cardiac damage in early left breast cancer patients: Risk factors, biological mechanisms, radiobiology, and dosimetric constraints
05 March 2012
Abstract: Today there is general awareness of the potential damage to the heart in left-sided (more than in right-sided) breast cancer radiotherapy (RT). Historical changes in tumor and heart doses ar...
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Angela Sardaro,
Maria Fonte Petruzzelli,
Maria Patrizia D’Errico,
Luca Grimaldi,
Giorgio Pili,
Maurizio Portaluri
et al.
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133-142
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| Original articles |
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Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature
23 November 2011
Abstract: Background: Radiotherapy of thoracic and chest wall tumors increases the long-term risk of cardiotoxicity, but the underlying mechanisms are unclear. Methods: Single doses of 2, 8, or 16Gy w...
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Ingar Seemann,
Karen Gabriels,
Nils L. Visser,
Saske Hoving,
Johannes A. te Poele,
Jeffrey F. Pol,
Marion J. Gijbels,
Ben J. Janssen,
Fijs W. van Leeuwen,
Mat J. Daemen,
Sylvia Heeneman,
Fiona A. Stewart
et al.
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143-150
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Effect of preoperative rescue concomitant FUN/XUN-based chemo-radiotherapy for neoadjuvant chemotherapy-refractory breast cancer
09 March 2012
Abstract: Even though tumor progression under neoadjuvant chemotherapy is uncommon, its locoregional management remains absolutely unclear. What is the best time for radical surgery or radiotherapy? “...
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Céline Bourgier,
Ismael Ghorbel,
Steve Heymann,
Manel Barhi,
Chafika Mazouni,
Abir Al Ghuzlan,
Corinne Balleyguier,
Hugo Marsiglia,
Suzette Delaloge
et al.
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151-154
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Long-term symptoms after radiotherapy of supraclavicular lymph nodes in breast cancer patients
10 February 2012
Abstract: Background and purpose: Irradiation of the supraclavicular lymph nodes has historically increased the risk of brachial plexopathy. We report long-term symptoms after modern radiotherapy (bas...
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Dan Lundstedt,
Magnus Gustafsson,
Gunnar Steineck,
David Alsadius,
Agnetha Sundberg,
Ulrica Wilderäng,
Erik Holmberg,
Karl-Axel Johansson,
Per Karlsson
et al.
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155-160
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Fat necrosis in women with early-stage breast cancer treated with accelerated partial breast irradiation (APBI) using interstitial brachytherapy
27 January 2012
Abstract: Purpose: To report the incidence of clinical, pathological and radiological fat necrosis (FN) in women treated with accelerated partial breast irradiation (APBI) using interstitial brachythe...
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Ashwini Budrukkar,
Vikas Jagtap,
Seema Kembhavi,
Anusheel Munshi,
Rakesh Jalali,
Tanuja Seth,
Vani Parmar,
Ritu Raj Upreti,
Rajendra Badwe,
Rajiv Sarin
et al.
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161-165
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How does imaging frequency and soft tissue motion affect the PTV margin size in partial breast and boost radiotherapy?
23 April 2012
Abstract: Purpose: This study investigates (i) the effect of verification protocols on treatment accuracy and PTV margins for partial breast and boost breast radiotherapy with short fractionation sche...
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Emma J. Harris,
Ellen M. Donovan,
Charlotte E. Coles,
Hans C.J. de Boer,
Andrew Poynter,
Christine Rawlings,
Gordon C. Wishart,
Philip M. Evans
et al.
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166-171
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Comparison of 3D conformal breast radiation treatment plans using the anisotropic analytical algorithm and pencil beam convolution algorithm
20 February 2012
Abstract: Purpose: To investigate (1) dosimetric differences between plans calculated using the anisotropic analytical algorithm (AAA) and pencil beam convolution (PBC) algorithm, (2) the plan quality...
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Sua Yoo,
Qiuwen Wu,
Jennifer O’Daniel,
Janet Horton,
Fang-Fang Yin
et al.
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172-177
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Reducing interobserver variation of boost-CTV delineation in breast conserving radiation therapy using a pre-operative CT and delineation guidelines
24 January 2012
Abstract: Aims: To investigate whether using a pre-operative CT scan (Preop-CT) (1) decreases interobserver variation of boost-CTV delineation in breast conserving therapy (BCT), and (2) influences th...
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Liesbeth J. Boersma,
Tomas Janssen,
Paula H.M. Elkhuizen,
Philip Poortmans,
Maurice van der Sangen,
Astrid N. Scholten,
Bianca Hanbeukers,
Joop C. Duppen,
Coen Hurkmans,
Corine van Vliet
et al.
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178-182
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Adaptive radiation therapy for breast IMRT-simultaneously integrated boost: Three-year clinical experience
27 January 2012
Abstract: Purpose: It has been shown that seroma volumes decrease during breast conserving radiotherapy in a significant percentage of patients. We report on our experience with an adaptive radiation ...
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Coen W. Hurkmans,
Ingrid Dijckmans,
Miranda Reijnen,
Jorien van der Leer,
Corine van Vliet-Vroegindeweij,
Maurice van der Sangen
et al.
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183-187
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On-line optimization of intraoperative electron beam radiotherapy of the breast
20 February 2012
Abstract: Purpose: To optimize the dose delivery to the breast lumpectomy target treated with intraoperative electron beam radiotherapy (IOERT). Materials and methods: Two tools have been developed in...
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Stefano Agostinelli,
Marco Gusinu,
Francesca Cavagnetto,
Stefania Garelli,
Michele Zeverino,
Marina Guenzi,
Renzo Corvò,
Gianni Taccini
et al.
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188-192
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Phase II trial of 3D-conformal accelerated partial breast irradiation: Lessons learned from patients and physicians’ evaluation
23 April 2012
Abstract: Introduction: The present study prospectively reported both physicians’ and patients’ assessment for toxicities, cosmetic assessment and patients’ satisfaction after 3D-conformal accelerated...
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Fares Azoury,
Steve Heymann,
Catalina Acevedo,
Marc Spielmann,
Philippe Vielh,
Jean-Rémi Garbay,
Alphonse G. Taghian,
Hugo Marsiglia,
Céline Bourgier
et al.
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193-198
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Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery
16 January 2012
Abstract: Purpose: To evaluate the impact of functional polymorphisms in genes related to DNA repair mechanisms (XRCC1, TP53, MSH2, MSH3, XPD), oxidative stress response (GSTP1, GSTA1, eNOS, SOD2) and...
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Salvatore Terrazzino,
Pierdaniele La Mattina,
Laura Masini,
Tina Caltavuturo,
Giuseppina Gambaro,
Pier Luigi Canonico,
Armando A. Genazzani,
Marco Krengli
et al.
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199-205
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TGFβ1 SNPs and radio-induced toxicity in prostate cancer patients
02 March 2012
Abstract: Background and purpose: We have performed a case-control study in 413 prostate cancer patients to test for association between TGFβ1 and the development of late normal-tissue toxicity among ...
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Laura Fachal,
Antonio Gómez-Caamaño,
Manuel Sánchez-García,
Ana Carballo,
Paula Peleteiro,
Ramón Lobato-Busto,
Ángel Carracedo,
Ana Vega
et al.
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206-209
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Phase II study of hypofractionated image-guided radiotherapy for localized prostate cancer: Outcomes of 55 Gy in 16 fractions at 3.4Gy per fraction
27 January 2012
Abstract: Purpose: To estimate the late morbidity of a novel, hypofractionated external beam radiotherapy schedule of 55Gy in 16 fractions (4 fractions/week, 3.4Gy per fraction) for localized prostate...
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Jackson S.Y. Wu,
Penelope M.A. Brasher,
Ali El-Gayed,
Nadeem Pervez,
Patricia T. Tai,
John Robinson,
David Skarsgard,
Kurian Joseph,
Michael A. Sia,
Robert G. Pearcey
et al.
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210-216
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Randomised trial of external beam radiotherapy alone or combined with high-dose-rate brachytherapy boost for localised prostate cancer
20 February 2012
Abstract: Background: A randomised phase-III trial compared external beam radiotherapy (EBRT) alone with EBRT combined with high-dose-rate brachytherapy boost (HDR-BTb) in localised prostate adenocarc...
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Peter J. Hoskin,
Ana M. Rojas,
Peter J. Bownes,
Gerry J. Lowe,
Peter J. Ostler,
Linda Bryant
et al.
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217-222
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Comparison between external beam radiotherapy (70Gy/74Gy) and permanent interstitial brachytherapy in 890 intermediate risk prostate cancer patients
07 March 2012
Abstract: Purpose: Aim of this analysis was to compare biochemical no evidence of disease (bNED) rates in intermediate-risk prostate-cancer patients treated at two centres of excellence using differen...
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Gregor Goldner,
Richard Pötter,
Jan J. Battermann,
Christian Kirisits,
Maximilian P. Schmid,
Samir Sljivic,
Marco van Vulpen
et al.
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223-227
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Outcomes following iodine-125 brachytherapy in patients with Gleason 7, intermediate risk prostate cancer: A population-based cohort study
13 February 2012
Abstract: Background and purpose: To evaluate outcome in patients with Gleason 7 prostate cancer treated with iodine-125 brachytherapy at the British Columbia Cancer Agency. Materials and methods: Bet...
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Christopher Herbert,
W. James Morris,
Mira Keyes,
Jeremy Hamm,
Vincent Lapointe,
Michael McKenzie,
Thomas Pickles,
Ingrid Spadinger
et al.
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228-232
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The effect of hormonal treatment on conspicuity of prostate cancer: Implications for focal boosting radiotherapy
24 January 2012
Abstract: Background and purpose: For focal boosting of prostate tumors, three questions are important regarding the use of hormonal therapy. Does prolonged hormonal treatment affect the conspicuity o...
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Greetje Groenendaal,
Marco van Vulpen,
Susanne R. Pereboom,
Davey Poelma-Tap,
Johannes G. Korporaal,
Evelyn Monninkhof,
Uulke A. van der Heide
et al.
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233-238
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Salvage radiotherapy after prostatectomy – What is the best time to treat?
28 November 2011
Abstract: Purpose: Salvage radiotherapy (SRT) is applied routinely in patients with biochemical relapse after radical prostatectomy (RP). However, only ∼30% of these patients achieve a durable respons...
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Alessandra Siegmann,
Dirk Bottke,
Julia Faehndrich,
Maike Brachert,
Gunnar Lohm,
Kurt Miller,
Detlef Bartkowiak,
Wolfgang Hinkelbein,
Thomas Wiegel
et al.
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239-243
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Clinical impact of margin reduction on late toxicity and short-term biochemical control for patients treated with daily on-line image guided IMRT for prostate cancer
28 November 2011
Abstract: To evaluate the impact of PTV reduction when delivering image-guided IMRT (IG-IMRT) for patients with prostate cancer. Between 2001 and 2007, 165 men were treated with daily IG-IMRT using a ...
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Gilles Crehange,
Celine Mirjolet,
Melanie Gauthier,
Etienne Martin,
Gilles Truc,
Karine Peignaux-Casasnovas,
Caroline Azelie,
Franck Bonnetain,
Suzanne Naudy,
Philippe Maingon
et al.
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244-246
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Urinary morbidity after permanent prostate brachytherapy – Impact of dose to the urethra vs. sources placed in close vicinity to the urethra
02 February 2012
Abstract: Background and purpose: The impact of the dose to the urethra and sources placed close to the urethra on urinary morbidity after permanent prostate brachytherapy (PPB) is not well known. Mat...
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Michael Pinkawa,
Richard Holy,
Marc D. Piroth,
Jens Klotz,
David Pfister,
Axel Heidenreich,
Michael J. Eble
et al.
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247-251
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Increasing the risk of late rectal bleeding after high-dose radiotherapy for prostate cancer: The case of previous abdominal surgery. Results from a prospective trial
23 April 2012
Abstract: Purpose: To evaluate and discuss the role of specific types of abdominal surgery (SURG) before radical radiation therapy as a risk factor for late rectal toxicity in prostate cancer patients...
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Riccardo Valdagni,
Vittorio Vavassori,
Tiziana Rancati,
Gianni Fellin,
Micaela Baccolini,
Carla Bianchi,
Emanuela Cagna,
Pietro Gabriele,
Floranna Mauro,
Loris Menegotti,
Angelo Filippo Monti,
Michele Stasi,
Claudio Fiorino
et al.
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252-255
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Urethra sparing – potential of combined Nickel–Titanium stent and intensity modulated radiation therapy in prostate cancer
26 December 2011
Abstract: Background and purpose: To investigate a novel method for sparing urethra in external beam radiotherapy of prostate cancer and to evaluate the efficacy of such a treatment in terms of tumour...
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Jakob Borup Thomsen,
Dennis Tideman Arp,
Jesper Carl
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256-260
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Methods of verifying the output of the treatment planning system used for high dose rate (HDR) prostate brachytherapy
18 November 2011
Abstract: Objectives: To investigate the relationships between the planning target volume (PTV) and the total reference air kerma (TRAK) required to irradiate the prostate using the Nucletron microSel...
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Aaron Huckle,
Bashar Al-Qaisieh,
Peter Bownes
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261-265
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Evaluation of the respiratory prostate motion with four-dimensional computed tomography scan acquisitions using three implanted markers
23 April 2012
Abstract: Background and purpose: During the irradiation of the prostate cancer, it is crucial to take into account the possible displacements in defining the planning target volume. The objective of ...
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Corina Udrescu,
Patrice Jalade,
Berardino de Bari,
Géraldine Michel-Amadry,
Olivier Chapet
et al.
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266-269
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Image-guided radiotherapy using surgical clips as fiducial markers after prostatectomy: A report of total setup error, required PTV expansion, and dosimetric implications
07 September 2011
Abstract: Purpose: To determine the total setup error and the required planning target volume (PTV) margin for prostate bed without image guided radiotherapy (IGRT), and to demonstrate the feasibility...
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Suisui Song,
Kamil M. Yenice,
Malgorzata Kopec,
Stanley L. Liauw
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270-274
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| Letter to the Editor |
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Incidence of skin recurrence after breast cancer surgery
24 January 2012
In a study of interobserver variations in delineating the breast for treatment planning, Reed et al. reported that interobserver differences were smallest at the breast skin surface, owing to the use ...
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Francesca Caparrotti,
Sindy Monnier,
Odile Fargier-Bochaton,
Mohamed Laouiti,
Palmira Caparrotti,
Nicolas Peguret,
Georges Vlastos,
Nam P. Nguyen,
Vincent Vinh-Hung
et al.
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275-277
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Important ESTRO dates
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