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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Health Economics in Radiation Oncology: Introducing the ESTRO HERO project
DOI: 10.1016/j.radonc.2011.12.026
Abstract: New evidence based regimens and novel high precision technology have reinforced the important role of radiotherapy in the management of cancer. Current data estimate that more than 50% of al...
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Yolande Lievens,
Cai Grau
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Full-length article
(In Press Corrected Proof)
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10 February 2012 |
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Long-term symptoms after radiotherapy of supraclavicular lymph nodes in breast cancer patients
DOI: 10.1016/j.radonc.2011.12.017
Abstract: Background and purpose: Irradiation of the supraclavicular lymph nodes has historically increased the risk of brachial plexopathy. We report long-term symptoms after modern radiotherapy (bas...
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Dan Lundstedt,
Magnus Gustafsson,
Gunnar Steineck,
David Alsadius,
Agnetha Sundberg,
Ulrica Wilderäng,
Erik Holmberg,
Karl-Axel Johansson,
Per Karlsson
et al.
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Full-length article
(In Press Corrected Proof)
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10 February 2012 |
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Results of carbon ion radiotherapy for head and neck cancer
DOI: 10.1016/j.radonc.2011.12.013
Abstract: Purpose: To evaluate the efficacy of carbon ion radiotherapy for head-and-neck cancer in a phase II clinical trial. Materials and methods: Between April 1997 and February 2006, 236 patients ...
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Jun-etsu Mizoe,
Azusa Hasegawa,
Keiichi Jingu,
Ryo Takagi,
Hiroki Bessyo,
Takamichi Morikawa,
Morio Tonoki,
Hiroshi Tsuji,
Tadashi Kamada,
Hirohiko Tsujii,
Yoshitaka Okamoto,
for Organizing Committee for the Working Group for Head Neck Cancer
et al.
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Full-length article
(In Press Corrected Proof)
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10 February 2012 |
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Radiographic changes after lung stereotactic ablative radiotherapy (SABR) – Can we distinguish recurrence from fibrosis? A systematic review of the literature
DOI: 10.1016/j.radonc.2011.12.018
Abstract: Background: Changes in lung density on computed tomography (CT) are common after stereotactic ablative radiotherapy (SABR) and can confound the early detection of recurrence. We performed a ...
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Kitty Huang,
Max Dahele,
Suresh Senan,
Matthias Guckenberger,
George B. Rodrigues,
Aaron Ward,
R. Gabriel Boldt,
David A. Palma
et al.
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Full-length article
(In Press Corrected Proof)
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06 February 2012 |
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Intensity-modulated radiotherapy in head and neck cancer: Results of the prospective study GORTEC 2004–03
DOI: 10.1016/j.radonc.2011.12.010
Abstract: Background and purpose: In 2003, the French Authority for Health (HAS) recommended the use of intensity modulated radiotherapy (IMRT) in prospective trial before its routine use. The Oncolog...
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Ivan Toledano,
Pierre Graff,
Antoine Serre,
Pierre Boisselier,
René-Jean Bensadoun,
Cécile Ortholan,
Pascal Pommier,
Séverine Racadot,
Gilles Calais,
Marc Alfonsi,
Veronique Favrel,
Philippe Giraud,
Michel Lapeyre
et al.
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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Managing a national radiation oncologist workforce: A workforce planning model
DOI: 10.1016/j.radonc.2011.12.025
Abstract: Purpose: The specialty of radiation oncology has experienced significant workforce planning challenges in many countries. Our purpose was to develop and validate a workforce-planning model t...
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Teri Stuckless,
Michael Milosevic,
Catherine de Metz,
Matthew Parliament,
Brent Tompkins,
Michael Brundage
et al.
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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Prognostic significance of the total dose of cisplatin administered during concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma
DOI: 10.1016/j.radonc.2011.12.022
Abstract: Background and purpose: Concurrent chemoradiotherapy (CRT) confers survival benefit over radiotherapy (RT) alone in the treatment of locoregionally advanced nasopharyngeal carcinoma (NPC). T...
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Herbert H. Loong,
Brigette B.Y. Ma,
Sing-Fai Leung,
Frankie Mo,
Edwin P. Hui,
Michael K. Kam,
Stephen L. Chan,
Brian K.H. Yu,
Anthony T.C. Chan
et al.
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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Urinary morbidity after permanent prostate brachytherapy – Impact of dose to the urethra vs. sources placed in close vicinity to the urethra
DOI: 10.1016/j.radonc.2011.12.011
Abstract: Background and purpose: The impact of the dose to the urethra and sources placed close to the urethra on urinary morbidity after permanent prostate brachytherapy (PPB) is not well known. Mat...
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Michael Pinkawa,
Richard Holy,
Marc D. Piroth,
Jens Klotz,
David Pfister,
Axel Heidenreich,
Michael J. Eble
et al.
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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A phase I/II study of gemcitabine-concurrent proton radiotherapy for locally advanced pancreatic cancer without distant metastasis
DOI: 10.1016/j.radonc.2011.12.029
Abstract: Purpose: We conducted the study to assess the feasibility and efficacy of gemcitabine-concurrent proton radiotherapy (GPT) for locally advanced pancreatic cancer (LAPC). Materials and method...
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Kazuki Terashima,
Yusuke Demizu,
Naoki Hashimoto,
Dongcun Jin,
Masayuki Mima,
Osamu Fujii,
Yasue Niwa,
Kento Takatori,
Naoto Kitajima,
Sachiyo Sirakawa,
Ku Yonson,
Yoshio Hishikawa,
Mitsuyuki Abe,
Ryohei Sasaki,
Kazuro Sugimura,
Masao Murakami
et al.
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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Out-of-field contributions for IMRT and volumetric modulated arc therapy measured using gafchromic films and compared to calculations using a superposition/convolution based treatment planning system
DOI: 10.1016/j.radonc.2011.12.030
Abstract: Purpose: To quantify the whole-body-dose delivered during the application of new techniques and compare them to the results obtained by treatment planning systems. The ultimate goal being th...
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Frank Van den Heuvel,
Gilles Defraene,
Wouter Crijns,
Ria Bogaerts
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy
DOI: 10.1016/j.radonc.2011.12.024
Abstract: The GYN GEC-ESTRO working group issued three parts of recommendations and highlighted the pivotal role of MRI for the successful implementation of 3D image-based cervical cancer brachytherap...
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Johannes C.A. Dimopoulos,
Peter Petrow,
Kari Tanderup,
Primoz Petric,
Daniel Berger,
Christian Kirisits,
Erik M. Pedersen,
Erik van Limbergen,
Christine Haie-Meder,
Richard Pötter
et al.
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Full-length article
(In Press Corrected Proof)
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02 February 2012 |
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Phase II study of hypofractionated image-guided radiotherapy for localized prostate cancer: Outcomes of 55 Gy in 16 fractions at 3.4 Gy per fraction
DOI: 10.1016/j.radonc.2011.12.020
Abstract: Purpose: To estimate the late morbidity of a novel, hypofractionated external beam radiotherapy schedule of 55Gy in 16 fractions (4 fractions/week, 3.4Gy per fraction) for localized prostate...
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Jackson S.Y. Wu,
Penelope M.A. Brasher,
Ali El-Gayed,
Nadeem Pervez,
Patricia T. Tai,
John Robinson,
David Skarsgard,
Kurian Joseph,
Michael A. Sia,
Robert G. Pearcey
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Dose–response analysis of acute oral mucositis and pharyngeal dysphagia in patients receiving induction chemotherapy followed by concomitant chemo-IMRT for head and neck cancer
DOI: 10.1016/j.radonc.2011.12.027
Abstract: Dose–response curves (DRCs) and the quantitative parameters describing these curves were generated for grade 3 oral mucositis and dysphagia in 144 patients using individual patient DVHs. Cur...
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Shreerang A. Bhide,
Sarah Gulliford,
Ulrike Schick,
Aisha Miah,
Shane Zaidi,
Katie Newbold,
Christopher M. Nutting,
Kevin J. Harrington
et al.
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Short communication
(In Press Corrected Proof)
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27 January 2012 |
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Late toxicities after conventional radiation therapy alone for nasopharyngeal carcinoma
DOI: 10.1016/j.radonc.2011.12.028
Abstract: Background and purpose: We sought to evaluate the nature and frequency of late toxicities in a cohort of nasopharyngeal cancer (NPC) patients treated with conventional radiotherapy alone. Me...
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Jeffrey Kit Loong Tuan,
Tam Cam Ha,
Whee Sze Ong,
Tian Rui Siow,
Ivan Weng Keong Tham,
Swee Peng Yap,
Terence Wee Kiat Tan,
Eu Tiong Chua,
Kam Weng Fong,
Joseph Tien Seng Wee
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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FDG–PET–CT reduces the interobserver variability in rectal tumor delineation
DOI: 10.1016/j.radonc.2011.12.016
Abstract: Background and purpose: Previously, we showed a good correlation between pathology and an automatically generated PET-contour in rectal cancer. This study analyzed the effect of the use of P...
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Jeroen Buijsen,
Jørgen van den Bogaard,
Hiska van der Weide,
Stephanie Engelsman,
Ruud van Stiphout,
Marco Janssen,
Geerard Beets,
Regina Beets-Tan,
Philippe Lambin,
Guido Lammering
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Fat necrosis in women with early-stage breast cancer treated with accelerated partial breast irradiation (APBI) using interstitial brachytherapy
DOI: 10.1016/j.radonc.2011.12.012
Abstract: Purpose: To report the incidence of clinical, pathological and radiological fat necrosis (FN) in women treated with accelerated partial breast irradiation (APBI) using interstitial brachythe...
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Ashwini Budrukkar,
Vikas Jagtap,
Seema Kembhavi,
Anusheel Munshi,
Rakesh Jalali,
Tanuja Seth,
Vani Parmar,
Ritu Raj Upreti,
Rajendra Badwe,
Rajiv Sarin
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Adaptive radiation therapy for breast IMRT-simultaneously integrated boost: Three-year clinical experience
DOI: 10.1016/j.radonc.2011.12.014
Abstract: Purpose: It has been shown that seroma volumes decrease during breast conserving radiotherapy in a significant percentage of patients. We report on our experience with an adaptive radiation ...
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Coen W. Hurkmans,
Ingrid Dijckmans,
Miranda Reijnen,
Jorien van der Leer,
Corine van Vliet-Vroegindeweij,
Maurice van der Sangen
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Incidence of skin recurrence after breast cancer surgery
DOI: 10.1016/j.radonc.2011.12.019
In a study of interobserver variations in delineating the breast for treatment planning, Reed et al. reported that interobserver differences were smallest at the breast skin surface, owing to the use ...
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Francesca Caparrotti,
Sindy Monnier,
Odile Fargier-Bochaton,
Mohamed Laouiti,
Palmira Caparrotti,
Nicolas Peguret,
Georges Vlastos,
Nam P. Nguyen,
Vincent Vinh-Hung
et al.
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Correspondence
(In Press Corrected Proof)
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24 January 2012 |
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The effect of hormonal treatment on conspicuity of prostate cancer: Implications for focal boosting radiotherapy
DOI: 10.1016/j.radonc.2011.12.007
Abstract: Background and purpose: For focal boosting of prostate tumors, three questions are important regarding the use of hormonal therapy. Does prolonged hormonal treatment affect the conspicuity o...
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Greetje Groenendaal,
Marco van Vulpen,
Susanne R. Pereboom,
Davey Poelma-Tap,
Johannes G. Korporaal,
Evelyn Monninkhof,
Uulke A. van der Heide
et al.
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Evaluating FDG uptake changes between pre and post therapy respiratory gated PET scans
DOI: 10.1016/j.radonc.2011.12.015
Abstract: Purpose: Whole body (3D) and respiratory gated (4D) FDG-PET/CT scans performed pre-radiotherapy (pre-RT) and post-radiotherapy (post-RT) were analyzed to investigate the impact of 4D PET in ...
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Michalis Aristophanous,
Yue Yong,
Jeffrey T. Yap,
Joseph H. Killoran,
Aaron M. Allen,
Ross I. Berbeco,
Aileen B. Chen
et al.
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Reducing interobserver variation of boost-CTV delineation in breast conserving radiation therapy using a pre-operative CT and delineation guidelines
DOI: 10.1016/j.radonc.2011.12.021
Abstract: Aims: To investigate whether using a pre-operative CT scan (Preop-CT) (1) decreases interobserver variation of boost-CTV delineation in breast conserving therapy (BCT), and (2) influences th...
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Liesbeth J. Boersma,
Tomas Janssen,
Paula H.M. Elkhuizen,
Philip Poortmans,
Maurice van der Sangen,
Astrid N. Scholten,
Bianca Hanbeukers,
Joop C. Duppen,
Coen Hurkmans,
Corine van Vliet
et al.
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Multivariate modeling of complications with data driven variable selection: Guarding against overfitting and effects of data set size
DOI: 10.1016/j.radonc.2011.12.006
Abstract: Purpose: Multivariate modeling of complications after radiotherapy is frequently used in conjunction with data driven variable selection. This study quantifies the risk of overfitting in a d...
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Arjen van der Schaaf,
Cheng-Jian Xu,
Peter van Luijk,
Aart A. van’t Veld,
Johannes A. Langendijk,
Cornelis Schilstra
et al.
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Outcome of four-dimensional stereotactic radiotherapy for centrally located lung tumors
DOI: 10.1016/j.radonc.2011.12.023
Abstract: Purpose: To assess local control, overall survival, and toxicity of four-dimensional, risk-adapted stereotactic body radiotherapy (SBRT) delivered while tracking respiratory motion in patien...
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Joost J. Nuyttens,
Noelle C. van der Voort van Zyp,
John Praag,
Shafak Aluwini,
Rob J. van Klaveren,
Cornelis Verhoef,
Peter M. Pattynama,
Mischa S. Hoogeman
et al.
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Full-length article
(In Press Corrected Proof)
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24 January 2012 |
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Hypofraction radiotherapy of liver tumor using cone beam computed tomography guidance combined with active breath control by long breath-holding
DOI: 10.1016/j.radonc.2011.11.007
Abstract: Background and purpose: To evaluate the feasibility and validity of cone beam computed tomography (CBCT) and active breath control (ABC) by long breath-holding in hypofraction radiotherapy o...
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Renming Zhong,
Jin Wang,
Xiaoqin Jiang,
Yinbo He,
Hong Zhang,
Nianyong Chen,
Sen Bai,
Feng Xu
et al.
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Full-length article
(In Press Corrected Proof)
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20 January 2012 |
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Bone marrow transplantation enhances trafficking of host-derived myelomonocytic cells that rescue intestinal mucosa after whole body radiation
DOI: 10.1016/j.radonc.2011.12.003
Abstract: Background: Bone marrow (BM)-derived cells were demonstrated within intestines after radiation damage and were reported to be responsible for intestine repair. However, there was a discrepan...
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Hui-Ju Ch’ang,
Li-Mei Lin,
Pu-Yuan Chang,
Chi-Wen Luo,
Ya-Hui Chang,
Chuan-Kai Chou,
Helen H. Chen
et al.
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Full-length article
(In Press Corrected Proof)
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19 January 2012 |
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Dose volume histogram analysis of focal liver reaction in follow-up multiphasic CT following stereotactic body radiotherapy for small hepatocellular carcinoma
DOI: 10.1016/j.radonc.2011.12.008
Abstract: Purpose: To investigate threshold dose (TD) of focal liver reaction (FLR) following stereotactic body radiotherapy (SBRT) for patients with hepatocellular carcinoma (HCC) and liver cirrhosis...
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Atsuya Takeda,
Yohei Oku,
Naoko Sanuki,
Etsuo Kunieda,
Naoyoshi Koike,
Yousuke Aoki,
Toshio Ohashi,
Shogo Iwabuchi,
Kentaro Takatsuka,
Toshiaki Takeda,
Akitomo Sugawara
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Stereotactic body radiation therapy in the treatment of multiple primary lung cancers
DOI: 10.1016/j.radonc.2011.12.005
Abstract: Background and purpose: Patients with multiple primary lung cancers (MPLC) present a therapeutic dilemma, particularly when they are at high risk for surgical resection. We evaluated the rol...
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Kimberly M. Creach,
Jeffrey D. Bradley,
Pawinee Mahasittiwat,
Clifford G. Robinson
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery
DOI: 10.1016/j.radonc.2011.12.002
Abstract: Purpose: To evaluate the impact of functional polymorphisms in genes related to DNA repair mechanisms (XRCC1, TP53, MSH2, MSH3, XPD), oxidative stress response (GSTP1, GSTA1, eNOS, SOD2) and...
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Salvatore Terrazzino,
Pierdaniele La Mattina,
Laura Masini,
Tina Caltavuturo,
Giuseppina Gambaro,
Pier Luigi Canonico,
Armando A. Genazzani,
Marco Krengli
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Control chart analysis of data from a multicenter monitor unit verification study
DOI: 10.1016/j.radonc.2011.11.016
Abstract: Background and purpose: This study aims to investigate the process of monitor unit verification using control charts. Control charts is a key tool within statistical process control (SPC), t...
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Fredrik Nordstöm,
Sacha af Wetterstedt,
Stefan Johnsson,
Crister Ceberg,
Sven Å.J. Bäck
et al.
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Full-length article
(In Press Corrected Proof)
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12 January 2012 |
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Repeat CT assessed CTV variation and PTV margins for short- and long-course pre-operative RT of rectal cancer
DOI: 10.1016/j.radonc.2011.11.011
Abstract: Purpose: To quantify the inter-fraction shape variation of the CTV in rectal-cancer patients treated with 5×5 (SCRT) and 25×2Gy (LCRT) and derive PTV margins. Methods and materials: Thirty-t...
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Jasper Nijkamp,
Maurits Swellengrebel,
Birgit Hollmann,
Rianne de Jong,
Corrie Marijnen,
Corine van Vliet-Vroegindeweij,
Baukelien van Triest,
Marcel van Herk,
Jan-Jakob Sonke
et al.
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Full-length article
(In Press Corrected Proof)
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12 January 2012 |
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Volumetric modulated arc therapy for nasopharyngeal carcinoma: A dosimetric comparison with TomoTherapy and step-and-shoot IMRT
DOI: 10.1016/j.radonc.2011.11.017
Abstract: Purpose: Volumetric modulated arc therapy (VMAT), a novel technique, employs a linear accelerator to conduct dynamic modulation rotation radiotherapy. The goal of this study was to compare V...
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Szu-Huai Lu,
Jason Chia-Hsien Cheng,
Sung-Hsin Kuo,
Jason Jeun-Shenn Lee,
Liang-Hsin Chen,
Jian-Kuen Wu,
Yu-Hsuan Chen,
Wan-Yu Chen,
Shu-Yu Wen,
Fok-Ching Chong,
Chien-Jang Wu,
Chun-Wei Wang
et al.
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Full-length article
(In Press Corrected Proof)
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11 January 2012 |
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Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells: Modulation of cellular signals regulating cell cycle and survival
DOI: 10.1016/j.radonc.2011.11.014
Abstract: Purpose: To analyze the (i) expression of AMPK in a variety of epithelial cancer cells, (ii) regulation of AMPK subunit expression by ionizing radiation (IR) and (iii) impact of AMPK on sign...
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Toran Sanli,
Yaryna Storozhuk,
Katja Linher-Melville,
Robert G. Bristow,
Keith Laderout,
Benoit Viollet,
James Wright,
Gurmit Singh,
Theodoros Tsakiridis
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Cone beam CT for organs motion evaluation in pediatric abdominal neuroblastoma
DOI: 10.1016/j.radonc.2011.11.009
Abstract: Background and purpose: To quantify the organ motion relative to bone in different breathing states in pediatric neuroblastoma using cone beam CT (CBCT) for better definition of the planning...
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Mohamed Soliman Nazmy,
Yasser Khafaga,
Amr Mousa,
Ehab Khalil
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging
DOI: 10.1016/j.radonc.2011.11.013
Abstract: Background and purpose: Studies of intradermal melanoma xenografts have suggested that dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) may be a useful method for assessing the...
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Kirsti Marie Øvrebø,
Tord Hompland,
Berit Mathiesen,
Einar K. Rofstad
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Urethra sparing – potential of combined Nickel–Titanium stent and intensity modulated radiation therapy in prostate cancer
DOI: 10.1016/j.radonc.2011.11.015
Abstract: Background and purpose: To investigate a novel method for sparing urethra in external beam radiotherapy of prostate cancer and to evaluate the efficacy of such a treatment in terms of tumour...
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Jakob Borup Thomsen,
Dennis Tideman Arp,
Jesper Carl
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Full-length article
(In Press Corrected Proof)
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26 December 2011 |
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Vertebral metastases reirradiation with volumetric-modulated arc radiotherapy
DOI: 10.1016/j.radonc.2011.11.005
Abstract: Purpose: To assess the feasibility, acute toxicity, clinical improvement, local control and survival for spinal metastatic patients re-irradiated using volumetric-modulated-arc-radiotherapy ...
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Pierina Navarria,
Pietro Mancosu,
Filippo Alongi,
Sara Pentimalli,
Angelo Tozzi,
Giacomo Reggiori,
Anna Maria Ascolese,
Stefano Arcangeli,
Francesca Lobefalo,
Riccardo Rodriguez Y. Baena,
Simona Castiglioni,
Federico Pessina,
Flavio Tancioni,
Armando Santoro,
Antonella Fogliata,
Luca Cozzi,
Marta Scorsetti
et al.
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Full-length article
(In Press Corrected Proof)
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22 December 2011 |
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The International Atomic Energy Agency (IAEA): An active role in the global fight against cancer
DOI: 10.1016/j.radonc.2011.10.004
The International Atomic Energy Agency (IAEA) is an independent, intergovernmental science and technology-based organization, in the United Nations, that serves as the global focal point for nuclear c...
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Eduardo Rosenblatt,
Eduardo Zubizarreta,
Jan Wondergem,
Elena Fidarova,
Joanna Izewska
et al.
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Editorial
(In Press Corrected Proof)
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14 December 2011 |
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The importance of bystander effects in radiation therapy in melanoma skin-cancer cells and umbilical-cord stromal stem cells
DOI: 10.1016/j.radonc.2011.11.002
Abstract: Purpose: To examine direct and bystander radiation-induced effects in normal umbilical-cord stromal stem cell (HCSSC) lines and in human cancer cells. Materials and methods: The UCSSC lines ...
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Jaime Gómez-Millán,
Iana Suly Santos Katz,
Virgínea de Araujo Farias,
Jose-Luis Linares-Fernández,
Jesús López-Peñalver,
Gustavo Ortiz-Ferrón,
Carmen Ruiz-Ruiz,
Francisco Javier Oliver,
José Mariano Ruiz de Almodóvar
et al.
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Full-length article
(In Press Corrected Proof)
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14 December 2011 |
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External validation of three dimensional conformal radiotherapy based NTCP models for patient-rated xerostomia and sticky saliva among patients treated with intensity modulated radiotherapy
DOI: 10.1016/j.radonc.2011.11.006
Abstract: Purpose: The purpose of this study was to investigate the ability of predictive models for patient-rated xerostomia (XER6M) and sticky saliva (STIC6M) at 6months after completion of primary ...
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Ivo Beetz,
Cornelis Schilstra,
Peter van Luijk,
Miranda E.M.C. Christianen,
Patricia Doornaert,
Henk P. Bijl,
Olga Chouvalova,
Edwin R. van den Heuvel,
Roel J.H.M. Steenbakkers,
Johannes A. Langendijk
et al.
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Full-length article
(In Press Corrected Proof)
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14 December 2011 |
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Does IGRT ensure target dose coverage of head and neck IMRT patients?
DOI: 10.1016/j.radonc.2011.09.024
Abstract: Purpose: To determine if image-guided radiotherapy (IGRT) ensures dose coverage to the target, and to assess the dosimetric impact of anatomic changes using megavoltage cone-beam CT (MVCBCT)...
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Pierre Graff,
Weigang Hu,
Sue S. Yom,
Jean Pouliot
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Full-length article
(In Press Corrected Proof)
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07 December 2011 |
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Clinical impact of margin reduction on late toxicity and short-term biochemical control for patients treated with daily on-line image guided IMRT for prostate cancer
DOI: 10.1016/j.radonc.2011.10.025
Abstract: To evaluate the impact of PTV reduction when delivering image-guided IMRT (IG-IMRT) for patients with prostate cancer. Between 2001 and 2007, 165 men were treated with daily IG-IMRT using a ...
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Gilles Crehange,
Celine Mirjolet,
Melanie Gauthier,
Etienne Martin,
Gilles Truc,
Karine Peignaux-Casasnovas,
Caroline Azelie,
Franck Bonnetain,
Suzanne Naudy,
Philippe Maingon
et al.
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Short communication
(In Press Corrected Proof)
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28 November 2011 |
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Accuracy of self-reported tobacco assessments in a head and neck cancer treatment population
DOI: 10.1016/j.radonc.2011.11.003
Abstract: Prospective analysis was performed of self-reported and biochemically confirmed tobacco use in 50 head and neck cancer patients during treatment. With 93.5% compliance to complete weekly sel...
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Graham W. Warren,
Susanne M. Arnold,
Joseph P. Valentino,
Thomas J. Gal,
Andrew J. Hyland,
Anurag K. Singh,
Vivek M. Rangnekar,
K. Michael Cummings,
James R. Marshall,
Mahesh R. Kudrimoti
et al.
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Short communication
(In Press Corrected Proof)
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28 November 2011 |
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Multimodality functional imaging of spontaneous canine tumors using 64Cu-ATSM and 18FDG PET/CT and dynamic contrast enhanced perfusion CT
DOI: 10.1016/j.radonc.2011.10.021
Abstract: Purpose: To compare the distribution and uptake of the hypoxia tracer 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) (64Cu-ATSM) PET/CT, FDG PET/CT and dynamic contrast enhanced perfusion CT ...
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Anders E. Hansen,
Annemarie T. Kristensen,
Ian Law,
Fintan J. McEvoy,
Andreas Kjær,
Svend A. Engelholm
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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In-gantry or remote patient positioning? Monte Carlo simulations for proton therapy centers of different sizes
DOI: 10.1016/j.radonc.2011.11.004
Abstract: Purpose: We estimated the potential advantage of remote positioning (RP) vs. in-room positioning (IP) for a proton therapy facility in terms of patient throughput. Materials and methods: Mon...
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Giovanni Fava,
Lamberto Widesott,
Francesco Fellin,
Maurizio Amichetti,
Valentina Viesi,
Antony J. Lomax,
Lydia Lederer,
Eugen B. Hug,
Claudio Fiorino,
Giovannella Salvadori,
Nadia Di Muzio,
Marco Schwarz
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise
DOI: 10.1016/j.radonc.2011.10.022
Abstract: Background and purpose: The Normal Tissue Complication Probability (NTCP) for rectum is usually defined for late rectal bleeding. This study calculates NTCP parameter values for additional r...
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Sarah L. Gulliford,
Mike Partridge,
Matthew R. Sydes,
Steve Webb,
Philip M. Evans,
David P. Dearnaley
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo
DOI: 10.1016/j.radonc.2011.10.023
Abstract: Purpose: Quercetin (3, 3,′ 4′, 5, 7 – five-flavonoids) is one of the main components of flavonoids, with multifunctions on immune function, anti-oxidation, anti-viral, anti-inflammatory, and...
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Chenghe Lin,
Yan Yu,
Hong-guan Zhao,
Aimin Yang,
Hong Yan,
Yali Cui
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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Salvage radiotherapy after prostatectomy – What is the best time to treat?
DOI: 10.1016/j.radonc.2011.10.024
Abstract: Purpose: Salvage radiotherapy (SRT) is applied routinely in patients with biochemical relapse after radical prostatectomy (RP). However, only ∼30% of these patients achieve a durable respons...
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Alessandra Siegmann,
Dirk Bottke,
Julia Faehndrich,
Maike Brachert,
Gunnar Lohm,
Kurt Miller,
Detlef Bartkowiak,
Wolfgang Hinkelbein,
Thomas Wiegel
et al.
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Full-length article
(In Press Corrected Proof)
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28 November 2011 |
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The potential benefit of swallowing sparing intensity modulated radiotherapy to reduce swallowing dysfunction: An in silico planning comparative study
DOI: 10.1016/j.radonc.2011.11.001
Abstract: Purpose: To apply recently developed predictive models for swallowing dysfunction to compare the predicted probabilities of swallowing dysfunction for standard intensity modulated radiothera...
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Hans Paul van der Laan,
Miranda E.M.C. Christianen,
Hendrik P. Bijl,
Cornelis Schilstra,
Johannes A. Langendijk
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature
DOI: 10.1016/j.radonc.2011.10.011
Abstract: Background: Radiotherapy of thoracic and chest wall tumors increases the long-term risk of cardiotoxicity, but the underlying mechanisms are unclear. Methods: Single doses of 2, 8, or 16Gy w...
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Ingar Seemann,
Karen Gabriels,
Nils L. Visser,
Saske Hoving,
Johannes A. te Poele,
Jeffrey F. Pol,
Marion J. Gijbels,
Ben J. Janssen,
Fijs W. van Leeuwen,
Mat J. Daemen,
Sylvia Heeneman,
Fiona A. Stewart
et al.
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Full-length article
(In Press Corrected Proof)
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23 November 2011 |
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A practical method of identifying data loss in 4DCT
DOI: 10.1016/j.radonc.2011.10.002
Abstract: Background and purpose: The design, testing and clinical implementation of a simple quality assurance tool which allows quick and accurate identification of regions of data loss and data int...
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David W. Smith,
Christopher Dean,
John Lilley
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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The seventh edition of the UICC/AJCC staging system for nasopharyngeal carcinoma is prognostically useful for patients treated with intensity-modulated radiotherapy from an endemic area in China
DOI: 10.1016/j.radonc.2011.10.009
Abstract: Purpose: To evaluate the 7th edition of the International Union against Cancer/American Joint Committee on Cancer (UICC/AJCC) staging system for nasopharyngeal carcinoma (NPC) in patients tr...
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Lei Chen,
Yan-Ping Mao,
Fang-Yun Xie,
Li-Zhi Liu,
Ying Sun,
Li Tian,
Ling-Long Tang,
Ai-Hua Lin,
Li Li,
Jun Ma
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Combined treatment of the immunoconjugate bivatuzumab mertansine and fractionated irradiation improves local tumour control in vivo
DOI: 10.1016/j.radonc.2011.10.013
Abstract: Background and purpose: To test whether BIWI 1 (bivatuzumab mertansine), an immunoconjugate of the humanized anti-CD44v6 monoclonal antibody BIWA 4 and the maytansinoid DM1, given simultaneo...
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Kristin Gurtner,
Franziska Hessel,
Wolfgang Eicheler,
Annegret Dörfler,
Daniel Zips,
Karl-Heinz Heider,
Mechthild Krause,
Michael Baumann
et al.
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Full-length article
(In Press Corrected Proof)
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21 November 2011 |
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Methods of verifying the output of the treatment planning system used for high dose rate (HDR) prostate brachytherapy
DOI: 10.1016/j.radonc.2011.09.022
Abstract: Objectives: To investigate the relationships between the planning target volume (PTV) and the total reference air kerma (TRAK) required to irradiate the prostate using the Nucletron microSel...
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Aaron Huckle,
Bashar Al-Qaisieh,
Peter Bownes
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Full-length article
(In Press Corrected Proof)
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18 November 2011 |
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IGRT induced dose burden for a variety of imaging protocols at two different anatomical sites
DOI: 10.1016/j.radonc.2011.10.005
Abstract: Background and purpose: Increase in positioning accuracy and treatment adaptation is supported by image guidance. The downside is the concomitant imaging dose. In this study, we report on th...
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Markus Stock,
Asa Palm,
Andreas Altendorfer,
Elisabeth Steiner,
Dietmar Georg
et al.
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Full-length article
(In Press Corrected Proof)
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18 November 2011 |
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Erratum to “Time course of hypothalamic-pituitary deficiency in adults receiving cranial radiotherapy for primary extrasellar brain tumors” [Radiother. Oncol. 99 (2011) 23–28]
DOI: 10.1016/j.radonc.2011.10.001
The Publisher regrets that in the above published article the authors’ first and family names appeared in reverse order. The authors’ names are presented in the correct order above.
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Sara Madaschi,
Claudio Fiorino,
Marco Losa,
Roberto Lanzi,
Elena Mazza,
Micaela Motta,
Lucia Perna,
Elena Brioschi,
Marina Scavini,
Michele Reni
et al.
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Erratum
(In Press Corrected Proof)
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07 November 2011 |
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Second cancer after radiotherapy, 1981–2007
DOI: 10.1016/j.radonc.2011.09.013
Abstract: Background and purpose: Today, there is growing concern about radiotherapy induced secondary malignancies. We analysed the incidence and dose dependence of second cancer. Material and method...
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Detlef Bartkowiak,
Nicole Humble,
Peter Suhr,
Juliane Hagg,
Katharina Mair,
Bernd Polivka,
Uwe Schneider,
Dirk Bottke,
Thomas Wiegel
et al.
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Full-length article
(In Press Corrected Proof)
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12 October 2011 |
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A method to adjust radiation dose–response relationships for clinical risk factors
DOI: 10.1016/j.radonc.2011.08.031
Abstract: Several clinical risk factors for radiation induced toxicity have been identified in the literature. Here, we present a method to quantify the effect of clinical risk factors on radiation do...
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Ane L. Appelt,
Ivan R. Vogelius
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Short communication
(In Press Corrected Proof)
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10 October 2011 |
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Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study
DOI: 10.1016/j.radonc.2011.08.009
Abstract: Background and purpose: The purpose of this large multicentre prospective cohort study was to identify which dose volume histogram parameters and pre-treatment factors are most important to ...
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Miranda E.M.C. Christianen,
Cornelis Schilstra,
Ivo Beetz,
Christina T. Muijs,
Olga Chouvalova,
Fred R. Burlage,
Patricia Doornaert,
Phil W. Koken,
C. René Leemans,
Rico N.P.M. Rinkel,
Marieke J. de Bruijn,
G.H. de Bock,
Jan L.N. Roodenburg,
Bernard F.A.M. van der Laan,
Ben J. Slotman,
Irma M. Verdonck-de Leeuw,
Hendrik P. Bijl,
Johannes A. Langendijk
et al.
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Full-length article
(In Press Corrected Proof)
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12 September 2011 |
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Image-guided radiotherapy using surgical clips as fiducial markers after prostatectomy: A report of total setup error, required PTV expansion, and dosimetric implications
DOI: 10.1016/j.radonc.2011.07.024
Abstract: Purpose: To determine the total setup error and the required planning target volume (PTV) margin for prostate bed without image guided radiotherapy (IGRT), and to demonstrate the feasibility...
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Suisui Song,
Kamil M. Yenice,
Malgorzata Kopec,
Stanley L. Liauw
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Full-length article
(In Press Corrected Proof)
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07 September 2011 |
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Statistical control of the spectral quality index in electron beams
DOI: 10.1016/j.radonc.2011.08.010
Abstract: Background and purpose: In radiotherapy with electron linear accelerators, it is mandatory to guarantee the stability of beam output spectra. In this work we study the quality control of the...
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José Manuel de la Vega,
Rafael Jesús Martínez-Luna,
Damián Guirado,
Manuel Vilches,
Antonio Miguel Lallena
et al.
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Full-length article
(In Press Corrected Proof)
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07 September 2011 |