Radiotherapy & Oncology
Volume 102, Issue 1 , Pages 4-9 , January 2012

Preoperative concomitant boost intensity-modulated radiotherapy with oral capecitabine in locally advanced mid-low rectal cancer: A phase II trial

  • Jin-luan Li

      Affiliations

    • Department of Radiation Oncology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • These authors contributed equally to this article.
    • ,
  • Jia-fu Ji

      Affiliations

    • Department of Gastrointestinal Surgery, Beijing Cancer Hospital and Institute, People’s Republic of China
    • These authors contributed equally to this article.
    • ,
  • Yong Cai

      Affiliations

    • Department of Radiation Oncology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • Corresponding Author InformationCorresponding author. Address: Department of Radiation Oncology, Peking University School of Oncology, Peking University Cancer Hospital, Beijing Cancer Hospital and Institute, 52 Fucheng Rd., Haidian District, Beijing 100142, People’s Republic of China.
    • ,
  • Xiao-fan Li

      Affiliations

    • Department of Radiation Oncology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Yong-heng Li

      Affiliations

    • Department of Radiation Oncology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Hao Wu

      Affiliations

    • Department of Radiation Oncology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Bo Xu

      Affiliations

    • Department of Radiation Oncology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Fang-yuan Dou

      Affiliations

    • Department of Pathology, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Zi-yu Li

      Affiliations

    • Department of Gastrointestinal Surgery, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Zhao-de Bu

      Affiliations

    • Department of Gastrointestinal Surgery, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Ai-wen Wu

      Affiliations

    • Department of Gastrointestinal Surgery, Beijing Cancer Hospital and Institute, People’s Republic of China
    • ,
  • Ivan W.K. Tham

      Affiliations

    • Department of Radiation Oncology, National University Cancer Institute, Singapore

Received 20 March 2011 ,Revised 29 July 2011 ,Accepted 29 July 2011.

  • Image Result

    Trial profile. Abbreviations: CRT, combination of concurrent boost intensity-modulated radiotherapy (GTV 50.6Gy/22 fractions, CTV 41.8Gy/22 fractions) with capecitabine (825mg/m2 twice daily 5days/wee

    Trial profile. Abbreviations: CRT, combination of concurrent boost intensity-modulated radiotherapy (GTV 50.6Gy/22 fractions, CTV 41.8Gy/22 fractions) with capecitabine (825mg/m2 twice daily 5days/week); TME, total mesorectal excision.

  • Image Result
    Kaplan–Meier survival curves.

    Kaplan–Meier survival curves.

☆ This trial is registered with chictr.org. Trial registry number: ChiCTR-TNC-10001094.

PII: S0167-8140(11)00408-7

doi: 10.1016/j.radonc.2011.07.030

Radiotherapy & Oncology
Volume 102, Issue 1 , Pages 4-9 , January 2012

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