Radiotherapy & Oncology
Volume 96, Issue 3 , Pages 325-327, September 2010

PET for radiation treatment planning of brain tumours

  • Anca-L. Grosu

      Affiliations

    • Department of Radiation Oncology, University of Freiburg, Germany
    • Corresponding Author InformationCorresponding author. Address: Department of Radiation Oncology, Albert Ludwigs University Freiburg, Robert Koch Str. 3, Freiburg 79106, Germany.
    • ,
  • Wolfgang A. Weber

      Affiliations

    • Department of Nuclear Medicine, University of Freiburg, Germany

Received 28 June 2010; received in revised form 1 August 2010; accepted 10 August 2010. published online 23 August 2010.

Abstract 

AA-PET (MET-PET and FET-PET) can be used for gross tumour volume (GTV) delineation in brain gliomas and for the differentiation between treatment-related changes (pseudo-progression, pseudo-regression) and residual/recurrent tumour. There are some data showing that MET-PET and (DOTATOC)-PET can be used for GTV delineation in meningiomas and glomus tumours. The role of PET in the visualization of the biological characteristics of the tumours: proliferation (FLT-PET), hypoxia (FMISO-PET) and angiogenesis/peptide expression (RGD-PET) should be investigated in future studies.

Keywords: Brain tumours, Radiation treatment planning, PET

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PII: S0167-8140(10)00461-5

doi:10.1016/j.radonc.2010.08.001

Radiotherapy & Oncology
Volume 96, Issue 3 , Pages 325-327, September 2010

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