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Feasibility of contrast-enhanced cone-beam CT for target localization and treatment monitoring

Jan RødalabCorresponding Author Informationemail address, Åste Søvikcd, Hege Kippenes Skogmod, Ingerid Skjei Knudtsene, Eirik Malinena

Received 19 March 2010; received in revised form 14 June 2010; accepted 3 July 2010. published online 28 July 2010.
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Abstract 

A dog with a spontaneous maxillary tumour was given 40Gy of fractionated radiotherapy. At five out of 10 fractions cone-beam CT (CBCT) imaging before and after administration of an iodinated contrast agent were performed. Contrast enhancement maps were overlaid on the pre-contrast CBCT images. The tumour was clearly visualized in the images thus produced.

a Department of Medical Physics, The Norwegian Radium Hospital, Oslo University Hospital, Norway

b Department of Physics, The Norwegian University of Science and Technology, Trondheim, Norway

c Department of Radiation Biology, The Norwegian Radium Hospital, Oslo University Hospital, Norway

d Department of Companion Animal Clinical Sciences, Norwegian School of Veterinary Science, Oslo, Norway

e Interventional Centre, Oslo University Hospital, Norway

Corresponding Author InformationCorresponding author. Address: Department of Medical Physics, The Norwegian Radium Hospital, Oslo University Hospital, Montebello, N-0310 Oslo, Norway.

PII: S0167-8140(10)00389-0

doi:10.1016/j.radonc.2010.07.006