Radiotherapy & Oncology
Volume 96, Issue 3 , Pages 308-310, September 2010

Quantitative analysis of PET studies

  • Wolfgang A. Weber

      Affiliations

    • Corresponding Author InformationAddress: Department of Nuclear Medicine, University Hospital Freiburg, Hugstetterstr. 55, 79106 Freiburg, Germany.

Department of Nuclear Medicine, University Hospital Freiburg, Germany

Received 4 June 2010; received in revised form 7 July 2010; accepted 7 July 2010. published online 26 July 2010.

Abstract 

Quantitative analysis can be included relatively easily in clinical PET-imaging protocols, but in order to obtain meaningful quantitative results one needs to follow a standardized protocol for image acquisition and data analysis. Important factors to consider are the calibration of the PET scanner, the radiotracer uptake time and the approach for definition of regions of interests. Using such standardized acquisition protocols quantitative parameters of tumor metabolism or receptor status can be derived from tracer kinetic analysis and simplified approaches such as calculation of standardized uptake values (SUVs).

Keywords: PET, Fluorodeoxyglucose, Quantitative analysis, Quality control, Standardized uptake values

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PII: S0167-8140(10)00387-7

doi:10.1016/j.radonc.2010.07.004

Radiotherapy & Oncology
Volume 96, Issue 3 , Pages 308-310, September 2010