Radiotherapy & Oncology
Volume 96, Issue 2 , Pages 153-160 , August 2010

Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group: Considerations and pitfalls in commissioning and applicator reconstruction in 3D image-based treatment planning of cervix cancer brachytherapy

  • Taran Paulsen Hellebust

      Affiliations

    • Department of Medical Physics, Oslo University Hospital, Norway
    • Corresponding Author InformationCorresponding author. Address: Department of Medical Physics, Division of Cancer and Surgery, Oslo University Hospital, Oslo, Norway.
  • ,
  • Christian Kirisits

      Affiliations

    • Department of Radiotherapy and Radiobiology, Medical University of Vienna, Austria
  • ,
  • Daniel Berger

      Affiliations

    • Department of Radiotherapy and Radiobiology, Medical University of Vienna, Austria
  • ,
  • José Pérez-Calatayud

      Affiliations

    • La Fe University Hospital, Valencia, Spain
  • ,
  • Marisol De Brabandere

      Affiliations

    • Department of Radiotherapy, University Hospital Gasthuisberg, Leuven, Belgium
  • ,
  • Astrid De Leeuw

      Affiliations

    • University Medical Centre Utrecht, The Netherlands
  • ,
  • Isabelle Dumas

      Affiliations

    • Department of Radiotherapy, Institut Gustav Roussy, Villejuif, France
  • ,
  • Robert Hudej

      Affiliations

    • Department of Radiotherapy, Institute of Oncology Ljubljana, Slovenia
  • ,
  • Gerry Lowe

      Affiliations

    • Mount Vernon Cancer Center, Northwood, UK
  • ,
  • Rachel Wills

      Affiliations

    • Mount Vernon Cancer Center, Northwood, UK
  • ,
  • Kari Tanderup

      Affiliations

    • Department of Oncology, Aarhus University Hospital, Denmark

Received 21 April 2010 ,Revised 7 June 2010 ,Accepted 8 June 2010.

References 

  1. Perez CA, Grigsby PW, Lockett MA, Chao KSC, Williamson J. Radiation therapy morbidity in carcinoma of the uterine cervix: dosimetric and clinical correlation. Int J Radiat Oncol Biol Phys. 1999;44:855–866
  2. Brooks S, Brownes P, Lowe G, Bryant L, Hoskin PJ. Cervical brachytherapy utilizing ring applicator: comparison of standard and conformal loading. Int J Radiat Oncol Biol Phys. 2005;63:934–939
  3. Haie-Meder C, Pötter R, van Limbergen E, et al. Recommendations from the Gynaecological (GYN) GEC ESTRO Working Group (Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV). Radiother Oncol. 2005;74:235–245
  4. Pötter R, Heie-Meder C, van Limbergen E, et al. Recommendations from the Gynaecological (GYN) GEC ESTRO Working Group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy – 3D volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol. 2006;78:67–77
  5. Pötter R, Dimopoulos J, Georg P, et al. Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer. Radiother Oncol. 2007;83:148–155
  6. Chajon E, Dumas I, Touleimat M, et al. Inverse planning approach for 3D MRI-based pulse-dose rate intracavitary brachytherapy in cervix cancer. Int J Radiat Oncol Biol Phys. 2007;69:955–961
  7. Lindegaard JC, Tanderup K, Nielsen SK, Haack S, Gelineck J. MRI-guided 3D optimization significantly improves DVH parameters of pulsed-dose-rate brachytherapy in locally advanced cervical cancer. Int J Radiat Oncol Biol Phys. 2008;71:756–764
  8. De Brabandere M, Mousa AG, Nulens A, Swinnen A, Van Limbergen E. Potential of dose optimisation in MRI-based PDR brachytherapy of cervix carcinoma. Radiother Oncol. 2008;88:217–226
  9. Lang S, Nulens A, Briot E, et al. Intercomparison of treatment concepts for MR image assisted brachytherapy of cervical carcinoma based on GYN GEC-ESTRO recommendations. Radiother Oncol. 2006;78:185–193
  10. Hellebust TP, Tanderup K, Bergstrand ES, Knutsen BH, Røislien J, Olsen DR. Reconstruction of the ring applicator set using CT imaging; impact of reconstruction method and applicator orientation. Phys Med Biol. 2007;52:4893–4904
  11. Tanderup K, Hellebust TP, Lang S, et al. Consequences of random and systematic reconstruction uncertainties in 3D image based brachytherapy in cervical cancer. Radiother Oncol. 2008;89:156–163
  12. Thomadsen B. Quality management for dosimetric treatment planning. In:  Thomadsen B editors. Achieving quality in brachytherapy. Medical science series. Bristol: Institute of Physics Publishing; 2000;p. 210–239
  13. Berger D, Dimopoulos J, Pötter R, Kirisits C. Direct reconstruction of the Vienna applicator on MR images. Radiother Oncol. 2009;93:347–351
  14. Kohr P, Siebert FA. Quality assurance of brachytherapy afterloaders using a multi-slit phantom. Phys Med Biol. 2007;52:387–391
  15. Wachowicz K, Thomas SD, Fallone BG. Characterization of the susceptibility artifact around a prostate brachytherapy seed in MRI. Med Phys. 2006;33:4459–4467
  16. Venselaar J, Pérez-Calatayud J, editors. A practical guide to quality control of brachytherapy equipment: European guidelines for quality assurance in radiotherapy. ESTRO Booklet No. 8. Brussel: European Society for Therapeutic Radiology and Oncology, ESTRO; 2004.
  17. Lin LL, Mutic S, Low DA, et al. Adaptive brachytherapy treatment planning for cervical cancer using FDG-PET. Int J Radiat Oncol Biol Phys. 2007;67:91–96
  18. Petric P, Dimopoulos J, Kirisits C, Berger D, Hudej R, Pötter R. Inter- and intraobserver variation in HR-CTV contouring: intercomparison of transverse and paratransverse image orientation in 3D-MRI assisted cervix cancer brachytherapy. Radiother Oncol. 2008;89:164–171
  19. Petric P, Hudej R, Rogelj P, Logar BZ. 3D T2-weighted fast recovery fast spin echo sequence MRI for target contouring in cervix cancer brachytherapy. Brachytherapy. 2008;7:109–110
  20. Haack S, Nielsen SK, Lindegaard JC, Gelineck J, Tanderup K. Applicator reconstruction in MRI 3D image-based dose planning of brachytherapy for cervical cancer. Radiother Oncol. 2009;91:187–193
  21. De Leeuw AAC, Moerland MA, Nomden C, Tersteeg RHA, Roesink JM, Jürgenliemk-Schulz IM. Applicator reconstruction and applicator shifts in 3D MR based PDR brachytherapy of cervical cancer. Radiother Oncol. 2009;93:341–346
  22. Bengtsson E, Vargas R, Nordell B, Lundell M. Markers to be used with MR compatible gynaecological brachytherapy applicators. Radiother Oncol. 2008;88:S427
  23. Perez-Calatayud J, Kuipers F, Ballester F, et al. Exclusive MRI-based tandem and colpostats reconstruction in gynaecological brachytherapy treatment planning. Radiother Oncol. 2009;91:181–186
  24. Chargari C, Magné N, Dumas I, et al. Physics contribution and clinical outcome with 3D-MRI-based pulsed-dose-rate intracavitary brachytherapy in cervical cancer patients. Int J Radiat Oncol Biol Phys. 2009;74:133–139
  25. Wills R, Lowe G, Inchley D, et al. Applicator reconstruction for HDR cervix treatment planning using images from 0.35T open MR scanner. Radiother Oncol. 2010;94:346–352

PII: S0167-8140(10)00368-3

doi: 10.1016/j.radonc.2010.06.004

Radiotherapy & Oncology
Volume 96, Issue 2 , Pages 153-160 , August 2010