Radiotherapy & Oncology
Volume 96, Issue 1 , Pages 38-42 , July 2010

Long-term experience with transrectal and transperineal implantations of fiducial gold markers in the prostate for position verification in external beam radiotherapy; feasibility, toxicity and quality of life

  • Maaike R. Moman

      Affiliations

    • Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    • Corresponding Author InformationCorresponding author. Address: Department of Radiation Oncology, Q00.118, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
    • ,
  • Uulke A. van der Heide

      Affiliations

    • Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Alexis N.T.J. Kotte

      Affiliations

    • Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • R. Jeroen A. van Moorselaar

      Affiliations

    • Department of Urology, VU Medical Center, Amsterdam, The Netherlands
    • ,
  • Gijsbert H. Bol

      Affiliations

    • Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Stefan P.G. Franken

      Affiliations

    • Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    • ,
  • Marco van Vulpen

      Affiliations

    • Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

Received 8 April 2009 ,Revised 22 February 2010 ,Accepted 23 February 2010.

References 

  1. van der Heide UA, Kotte AN, Dehnad H, Hofman P, Lagenijk JJ, van Vulpen M. Analysis of fiducial marker-based position verification in the external beam radiotherapy of patients with prostate cancer. Radiother Oncol. 2007;82:38–45
  2. McNair HA, Hansen VN, Parker CC, et al. A comparison of the use of bony anatomy and internal markers for offline verification and an evaluation of the potential benefit of online and offline verification protocols for prostate radiotherapy. Int J Radiat Oncol Biol Phys. 2008;71:41–50
  3. van der Vight LP, van Lin EN, Spitters-Post I, Visser AG, Louwe RJ. Off-line setup corrections only marginally reduce the number of on-line corrections for prostate radiotherapy using implanted gold markers. Radiother Oncol. 2009;90:359–366
  4. Kotte AN, Hofman P, Lagendijk JJ, van Vulpen M, van der Heide UA. Intrafraction motion of the prostate during external-beam radiation therapy: analysis of 427 patients with implanted fiducial markers. Int J Radiat Oncol Biol Phys. 2007;69:419–425
  5. Lips I, Dehnad H, Kruger AB, van Moorselaar J, et al. Health-related quality of life in patients with locally advanced prostate cancer after 76 Gy intensity-modulated radiotherapy vs. 70 Gy conformal radiotherapy in a prospective and longitudinal study. Int J Radiat Oncol Biol Phys. 2007;69:656–661
  6. Lips IM, Dehnad H, van Gils CH, Boeken Kruger AE, van der Heide UA, van Vulpen M. High-dose intensity-modulated radiotherapy for prostate cancer using daily fiducial marker-based position verification: acute and late toxicity in 331 patients. Radiat Oncol. 2008;3:15
  7. Al Mamgani A, van Putten WL, Heemsbergen WD, van Leenders GJ, Slot A, Dielwart MF, et al. Update of Dutch multicenter dose–escalation trial of radiotherapy for localized prostate cancer. Int J Radiat Oncol Biol Phys. 2008;72:980–988
  8. Poggi MM, Gant DA, Sewchand W, Warlick WB. Marker seed migration in prostate localization. Int J Radiat Oncol Biol Phys. 2003;56:1248–1251
  9. Nichol AM, Brock KK, Lockwood GA, et al. A magnetic resonance imaging study of prostate deformation relative to implanted gold fiducial markers. Int J Radiat Oncol Biol Phys. 2007;67:48–56
  10. Dehnad H, Nederveen AJ, van der Heide UA, van Moorselaar RJ, Hofman P, Lagendijk JJ. Clinical feasibility study for the use of implanted gold seeds in the prostate as reliable positioning markers during megavoltage irradiation. Radiother Oncol. 2003;67:295–302
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  15. Langenhuijsen JF, van Lin EN, Kiemeney LA, et al. Ultrasound-guided transrectal implantation of gold markers for prostate localization during external beam radiotherapy: complication rate and risk factors. Int J Radiat Oncol Biol Phys. 2007;69:671–676
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  20. Kitamura K, Shirato H, Shimizu S, et al. Registration accuracy and possible migration of internal fiducial gold marker implanted in prostate and liver treated with real-time tumor-tracking radiation therapy (RTRT). Radiother Oncol. 2002;62:275–281
  21. Pouliot J, Aubin M, Langen KM, et al. (Non)-migration of radiopaque markers used for on-line localization of the prostate with an electronic portal imaging device. Int J Radiat Oncol Biol Phys. 2003;56:862–866

PII: S0167-8140(10)00132-5

doi: 10.1016/j.radonc.2010.02.027

Radiotherapy & Oncology
Volume 96, Issue 1 , Pages 38-42 , July 2010

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