Radiotherapy & Oncology
Volume 95, Issue 2 , Pages 240-244 , May 2010

Analysis of dose–volume histogram parameters for radiation pneumonitis after definitive concurrent chemoradiotherapy for esophageal cancer

  • Hirofumi Asakura

      Affiliations

    • Division of Radiation Oncology
    • Corresponding Author InformationCorresponding author. Address: Division of Radiation Oncology, Shizuoka Cancer Center Hospital, 1007 Shimonagakubo, Nagaizumi, Shizuoka 411-8777, Japan.
    • ,
  • Takayuki Hashimoto

      Affiliations

    • Division of Radiation Oncology
    • ,
  • Sadamoto Zenda

      Affiliations

    • Division of Radiation Oncology
    • Division of Radiation Oncology, National Cancer Center Hospital East, Chiba, Japan
    • ,
  • Hideyuki Harada

      Affiliations

    • Division of Radiation Oncology
    • ,
  • Koichi Hirakawa

      Affiliations

    • Division of Radiation Oncology
    • Department of Radiology, Faculty of Medicine, Saga University, Saga, Japan
    • ,
  • Masashi Mizumoto

      Affiliations

    • Division of Radiation Oncology
    • ,
  • Kazuhisa Furutani

      Affiliations

    • Division of Radiation Oncology
    • ,
  • Shuichi Hironaka

      Affiliations

    • Division of Gastrointestinal Oncology; and
    • ,
  • Hiroshi Fuji

      Affiliations

    • Division of Proton Therapy, Shizuoka Cancer Center Hospital, Shizuoka, Japan
    • ,
  • Shigeyuki Murayama

      Affiliations

    • Division of Proton Therapy, Shizuoka Cancer Center Hospital, Shizuoka, Japan
    • ,
  • Narikazu Boku

      Affiliations

    • Division of Gastrointestinal Oncology; and
    • ,
  • Tetsuo Nishimura

      Affiliations

    • Division of Radiation Oncology

Received 3 February 2009 ,Revised 7 February 2010 ,Accepted 8 February 2010.

References 

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  2. Hernando ML, Marks LB, Bentel GC, et al. Radiation-induced pulmonary toxicity: a dose–volume histogram analysis in 201 patients with lung cancer. Int J Radiat Oncol Biol Phys. 2001;51:650–659
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  4. Tsujino K, Hirota S, Endo M, et al. Predictive value of dose–volume histogram parameters for predicting radiation pneumonitis after concurrent chemoradiation for lung cancer. Int J Radiat Oncol Biol Phys. 2003;55:110–115
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  10. Kwa SL, Lebesque JV, Theuws JC, et al. Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys. 1998;42:1–9
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  13. Chang DT, Olivier KR, Morris CG, et al. The impact of heterogeneity correction on dosimetric parameters that predict for radiation pneumonitis. Int J Radiat Oncol Biol Phys. 2006;65:125–131
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  15. Dehing-Oberije C, De Ruysscher D, van Baardwijk A, Yu S, Rao B, Lambin P. The importance of patient characteristics for the prediction of radiation-induced lung toxicity. Radiother Oncol. 2009;91:421–426
  16. Kleinberg L, Forastiere AA. Chemoradiation in the management of esophageal cancer. J Clin Oncol. 2007;25:4110–4117
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  18. Ishikura S, Nihei K, Ohtsu A, et al. Long-term toxicity after definitive chemoradiotherapy for squamous cell carcinoma of the thoracic esophagus. J Clin Oncol. 2003;21:2697–2702
  19. Wang SL, Liao Z, Vaporciyan AA, et al. Investigation of clinical and dosimetric factors associated with postoperative pulmonary complications in esophageal cancer patients treated with concurrent chemoradiotherapy followed by surgery. Int J Radiat Oncol Biol Phys. 2006;64:692–699
  20. Akobeng AK. Understanding diagnostic tests 3: receiver operating characteristic curves. Acta Paediatr. 2007;96:644–647
  21. Wang S, Liao Z, Wei X, et al. Association between systemic chemotherapy before chemoradiation and increased risk of treatment-related pneumonitis in esophageal cancer patients treated with definitive chemoradiotherapy. J Thorac Oncol. 2008;3:277–282
  22. Japan Esophageal Society. Comprehensive registry of esophageal cancer in Japan. Available at http://esophagus.jp/crec.html.

PII: S0167-8140(10)00083-6

doi: 10.1016/j.radonc.2010.02.006

Radiotherapy & Oncology
Volume 95, Issue 2 , Pages 240-244 , May 2010

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