Radiotherapy & Oncology
Volume 95, Issue 2 , Pages 149-152, May 2010

IMRT-based optimization approaches for volumetric modulated single arc radiotherapy planning

Department of Radiotherapy, University Hospital Leuven, Belgium

Received 23 July 2009; received in revised form 8 January 2010; accepted 17 January 2010. published online 22 February 2010.

Abstract 

This paper reports on an evaluation of 5 RapidArc® optimization approaches vs IMRT. This study includes 11 patients with adenocarcinoma of the prostate. Rectal Normal Tissue Complication Probability is used as a constraint in a dose escalation. RapidArc® rectal NTCP’s are lower than those of IMRT (p=0.007). This allows a mean dose escalation of 2.1Gy([0.7Gy,3.5Gy]).

Keywords: RapidArc®, VMAT, Dose escalation, Prostate cancer

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PII: S0167-8140(10)00063-0

doi:10.1016/j.radonc.2010.01.012

Radiotherapy & Oncology
Volume 95, Issue 2 , Pages 149-152, May 2010

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