Comparison between CT- and FDG-PET-defined target volumes for radiotherapy planning in head-and-neck cancers

Henriques de Figueiredo, Bénédicte; Barret, Olivier; Demeaux, Hélène; Lagarde, Philippe; De-Mones-Del-Pujol, Erwan; Kantor, Guy; de Clermont-Gallerande, Henri; Richaud, Pierre; Fernandez, Philippe

doi:10.1016/j.radonc.2009.09.010

« Previous Next »Radiotherapy & Oncology
Volume 93, Issue 3 , Pages 479-482, December 2009

Comparison between CT- and FDG-PET-defined target volumes for radiotherapy planning in head-and-neck cancers

Bénédicte Henriques de Figueiredo
- Department of Nuclear Medicine; and
- Corresponding author. Address: Department of Radiotherapy, Institut Bergonié, 229, cours de l’Argonne, 33076 Bordeaux Cedex, France.
Olivier Barret
- Department of Nuclear Medicine; and
Hélène Demeaux
- Department of Clinical Oncology and Radiation Oncology, CHRU Bordeaux, France
Philippe Lagarde
- Department of Radiation Oncology, Institut Bergonié, Bordeaux, France
Erwan De-Mones-Del-Pujol
- Department of Oto-rhino-laryngology, CHRU Bordeaux, France
Guy Kantor
- Department of Radiation Oncology, Institut Bergonié, Bordeaux, France
Henri de Clermont-Gallerande
- Department of Nuclear Medicine; and
Pierre Richaud
- Department of Radiation Oncology, Institut Bergonié, Bordeaux, France
Philippe Fernandez
- Department of Nuclear Medicine; and

Received 28 June 2009; received in revised form 25 September 2009; accepted 29 September 2009. published online 02 November 2009.

Abstract

Nine patients with head-and-neck cancer underwent computerized tomography (CT) simulation and [¹⁸F]-fluorodeoxyglucose positron emission tomography (FDG-PET) to compare the radiotherapy target volumes. The PET volumes were delineated with an automatic segmentation based on the source-to-background ratio. The volume comparison showed a reduction and qualitative discrepancies between the PET- and CT-volumes.

Keywords: Radiotherapy planning, FDG-PET, Head-and-neck cancer, Target volumes, Automatic segmentation