Radiotherapy & Oncology
Volume 93, Issue 2 , Pages 226-233 , November 2009

Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer

  • Dirk Wolff

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • Corresponding Author InformationCorresponding author. Address: UMM Universitätsmedizin Mannheim, Universitätsklinik für Strahlentherapie und Radioonkologie, Theodor-Kutzer Ufer 1-3, 68167 Mannheim, Germany.
    • ,
  • Florian Stieler

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Grit Welzel

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Friedlieb Lorenz

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Yasser Abo-Madyan

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • Department of Oncology (NEMROCK), Kasr-El-Einy Hospital, Cairo University, Egypt
    • ,
  • Sabine Mai

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Carsten Herskind

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Martin Polednik

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Volker Steil

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Frederik Wenz

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany
    • ,
  • Frank Lohr

      Affiliations

    • Department of Radiation Oncology of the University Medical Center Mannheim, University of Heidelberg, Germany

Received 1 February 2009 ,Revised 28 July 2009 ,Accepted 2 August 2009.

References 

  1. Peeters ST, Heemsbergen WD, van Putten WL, et al. Acute and late complications after radiotherapy for prostate cancer: results of a multicenter randomized trial comparing 68Gy to 78Gy. Int J Radiat Oncol Biol Phys. 2005;61:1019–1034
  2. Pollack A, Zagars GK, Smith LG, et al. Preliminary results of a randomized radiotherapy dose-escalation study comparing 70Gy with 78Gy for prostate cancer. J Clin Oncol. 2000;18:3904–3911
  3. Kupelian PA, Ciezki J, Reddy CA, et al. Effect of increasing radiation doses on local and distant failures in patients with localized prostate cancer. Int J Radiat Oncol Biol Phys. 2008;71:16–22
  4. South CP, Khoo VS, Naismith O, et al. A comparison of treatment planning techniques used in two randomised UK external beam radiotherapy trials for localised prostate cancer. Clin Oncol (R Coll Radiol). 2008;20:15–21
  5. Zelefsky MJ, Fuks Z, Happersett L, et al. Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer. Radiother Oncol. 2000;55:241–249
  6. De Meerleer G, Vakaet L, Meersschout S, et al. Intensity-modulated radiotherapy as primary treatment for prostate cancer: acute toxicity in 114 patients. Int J Radiat Oncol Biol Phys. 2004;60:777–787
  7. De Meerleer GO, Vakaet LA, De Gersem WR, et al. Radiotherapy of prostate cancer with or without intensity modulated beams: a planning comparison. Int J Radiat Oncol Biol Phys. 2000;47:639–648
  8. Zelefsky MJ, Levin EJ, Hunt M, et al. Incidence of late rectal and urinary toxicities after three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for localized prostate cancer. Int J Radiat Oncol Biol Phys. 2008;70:1124–1129
  9. Brahme A, Roos JE, Lax I. Solution of an integral equation encountered in rotation therapy. Phys Med Biol. 1982;27:1221–1229
  10. Bratengeier K. 2-Step IMAT and 2-Step IMRT in three dimensions. Med Phys. 2005;32:3849–3861
  11. Otto K. Volumetric modulated arc therapy: IMRT in a single gantry arc. Med Phys. 2008;35:310–317
  12. Yu CX. Intensity-modulated arc therapy with dynamic multileaf collimation: an alternative to tomotherapy. Phys Med Biol. 1995;40:1435–1449
  13. Yu CX, Li XA, Ma L, et al. Clinical implementation of intensity-modulated arc therapy. Int J Radiat Oncol Biol Phys. 2002;53:453–463
  14. Duthoy W, De Gersem W, Vergote K, et al. Clinical implementation of intensity-modulated arc therapy (IMAT) for rectal cancer. Int J Radiat Oncol Biol Phys. 2004;60:794–806
  15. Duthoy W, De Gersem W, Vergote K, et al. Whole abdominopelvic radiotherapy (WAPRT) using intensity-modulated arc therapy (IMAT): first clinical experience. Int J Radiat Oncol Biol Phys. 2003;57:1019–1032
  16. Bedford JL, Nordmark Hansen V, McNair HA, et al. Treatment of lung cancer using volumetric modulated arc therapy and image guidance: a case study. Acta Oncol. 2008;47:1438–1443
  17. Carol M, Grant WH, Bleier AR, et al. The field-matching problem as it applies to the peacock three dimensional conformal system for intensity modulation. Int J Radiat Oncol Biol Phys. 1996;34:183–187
  18. Dobler B, Lorenz F, Wertz H, et al. Intensity-modulated radiation therapy (IMRT) with different combinations of treatment-planning systems and linacs: issues and how to detect them. Strahlenther Onkol. 2006;182:481–488
  19. Saw CB, Ayyangar KM, Zhen W, et al. Quality assurance procedures for the Peacock system. Med Dosim. 2001;26:83–90
  20. Xia P, Pickett B, Vigneault E, et al. Forward or inversely planned segmental multileaf collimator IMRT and sequential tomotherapy to treat multiple dominant intraprostatic lesions of prostate cancer to 90Gy. Int J Radiat Oncol Biol Phys. 2001;51:244–254
  21. Al-Ghazi M, Kwon R, Kuo J, et al. The University of California, Irvine experience with tomotherapy using the Peacock system. Med Dosim. 2001;26:17–27
  22. Nizin PS, Kania A, Ayyangar K. Basic concepts of CORVUS dose model. Med Dosim. 2001;26:65–69
  23. Fogliata A, Nicolini G, Alber M, et al. IMRT for breast, a planning study. Radiother Oncol. 2005;76:300–310
  24. Alber M, Nusslin F. An objective function for radiation treatment optimization based on local biological measures. Phys Med Biol. 1999;44:479–493
  25. Bar W, Schwarz M, Alber M, et al. A comparison of forward and inverse treatment planning for intensity-modulated radiotherapy of head and neck cancer. Radiother Oncol. 2003;69:251–258
  26. (RTOG) Rtog. 95-02 RTOG. Phase IB Study of Radiosurgery and Etanidazole (SR-2508) for the treatment of recurrent primary brain tumors orCNS metastases, 1997:1-26.
  27. Dearnaley DP, Khoo VS, Norman AR, et al. Comparison of radiation side-effects of conformal and conventional radiotherapy in prostate cancer: a randomised trial. Lancet. 1999;353:267–272
  28. Kuban DA, Tucker SL, Dong L, et al. Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer. Int J Radiat Oncol Biol Phys. 2008;70:67–74
  29. Fiorino C, Cozzarini C, Vavassori V, et al. Relationships between DVHs and late rectal bleeding after radiotherapy for prostate cancer: analysis of a large group of patients pooled from three institutions. Radiother Oncol. 2002;64:1–12
  30. Greco C, Mazzetta C, Cattani F, et al. Finding dose-volume constraints to reduce late rectal toxicity following 3D-conformal radiotherapy (3D-CRT) of prostate cancer. Radiother Oncol. 2003;69:215–222
  31. Tucker SL, Cheung R, Dong L, et al. Dose-volume response analyses of late rectal bleeding after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys. 2004;59:353–365
  32. Vordermark D, Schwab M, Ness-Dourdoumas R, et al. Association of anorectal dose-volume histograms and impaired fecal continence after 3D conformal radiotherapy for carcinoma of the prostate. Radiother Oncol. 2003;69:209–214
  33. Hall EJ, Wuu CS. Radiation-induced second cancers: the impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys. 2003;56:83–88
  34. Hong TS, Craft DL, Carlsson F, Bortfeld TR. Multicriteria optimization in intensity-modulated radiation therapy treatment planning for locally advanced cancer of the pancreatic head. Int J Radiat Oncol Biol Phys. 2008;72:1208–1214
  35. Bortfeld T, Webb S. Single-Arc IMRT?. Phys Med Biol. 2009;54:N9–N20
  36. Coselmon MM, Moran JM, Radawski JD, Fraass BA. Improving IMRT delivery efficiency using intensity limits during inverse planning. Med Phys. 2005;32:1234–1245
  37. Yang J, Li J, Chen L, et al. Dosimetric verification of IMRT treatment planning using Monte Carlo simulations for prostate cancer. Phys Med Biol. 2005;50:869–878
  38. Roland TF, Stathakis S, Ramer R, Papanikolaou N. Measurement and comparison of skin dose for prostate and head-and-neck patients treated on various IMRT delivery systems. Appl Radiat Isot. 2008;66:1844–1849
  39. Mackie TR, Balog J, Ruchala K, et al. Tomotherapy. Semin Radiat Oncol. 1999;9:108–117
  40. Fuss M, Shi C, Papanikolaou N. Tomotherapeutic stereotactic body radiation therapy: Techniques and comparison between modalities. Acta Oncol. 2006;45:953–960
  41. Ramsey CR, Scaperoth D, Seibert R, et al. Image-guided helical tomotherapy for localized prostate cancer: technique and initial clinical observations. J Appl Clin Med Phys. 2007;8:2320
  42. Cao D, Holmes TW, Afghan MK, Shepard DM. Comparison of plan quality provided by intensity-modulated arc therapy and helical tomotherapy. Int J Radiat Oncol Biol Phys. 2007;69:240–250
  43. Palma D, Vollans E, James K, et al. Volumetric Modulated Arc Therapy for Delivery of Prostate Radiotherapy: Comparison with Intensity-Modulated Radiotherapy and Three-Dimensional Conformal Radiotherapy. Int J Radiat Oncol Biol Phys. 2008;72:996–1001
  44. Shaffer R, Morris WJ, Moiseenko V, et al. Volumetric Modulated Arc Therapy and Conventional Intensity-modulated Radiotherapy for Simultaneous Maximal Intraprostatic Boost: a Planning Comparison Study. Clin Oncol (R Coll Radiol). 2009;21:401–404
  45. Cozzi L, Dinshaw KA, Shrivastava SK, et al. A treatment planning study comparing volumetric arc modulation with RapidArc and fixed field IMRT for cervix uteri radiotherapy. Radiother Oncol. 2008;89:180–191
  46. Clivio A, Fogliata A, Franzetti-Pellanda A, et al. Volumetric-modulated arc radiotherapy for carcinomas of the anal canal: A treatment planning comparison with fixed field IMRT. Radiother Oncol. 2009;92:118–124
  47. Vanetti E, Clivio A, Nicolini G, et al. Volumetric modulated arc radiotherapy for carcinomas of the oro-pharynx, hypo-pharynx and larynx: A treatment planning comparison with fixed field IMRT. Radiother Oncol. 2009;92:111–117
  48. Fogliata A, Clivio A, Nicolini G, et al. Intensity modulation with photons for benign intracranial tumours: a planning comparison of volumetric single arc, helical arc and fixed gantry techniques. Radiother Oncol. 2008;89:254–262

PII: S0167-8140(09)00447-2

doi: 10.1016/j.radonc.2009.08.011

Radiotherapy & Oncology
Volume 93, Issue 2 , Pages 226-233 , November 2009

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