Radiotherapy & Oncology
Volume 93, Issue 3 , Pages 458-461 , December 2009

Phase I study of concurrent selective lymph node late course accelerated hyper-fractionated radiotherapy and Capecitabine, Cisplatin for locally advanced esophageal squamous cell carcinoma

  • Bao-sheng Li

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Tao Zhou

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Zhong-tang Wang

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Hong-sheng Li

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Hong-fu Sun

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Zhi-cheng Zhang

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Hai-qun Lin

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Yu-mei Wei

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • He-yi Gong

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Wei Huang

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Yan Yi

      Affiliations

    • Sixth Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • ,
  • Li-ying Wang

      Affiliations

    • Department of Medicine Oncology, Shandong Cancer Hospital, Shandong Province, PR China
    • Corresponding Author InformationCorresponding author. Address: Department of Medicine Oncology, Shandong Cancer Hospital, No. 440, Ji-Yan Rd., Ji-Nan, Shandong Province, PR China.

Received 24 April 2009 ,Revised 1 August 2009 ,Accepted 11 August 2009.

References 

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  2. Minsky BD, Pajak TF, Ginsberg RJ, et al. INT0123 (Radiation Therapy Oncology Group 94-05) Phase III trial of combined-modality therapy for esophageal cancer: high-dose versus standard-dose radiation therapy. J Clin Oncol. 2002;20:1167–1174
  3. Cooper J, Guo M, Herskovic A, et al. Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group. JAMA. 1999;281:1623–1627
  4. Zhao KL, Shi XH, Jiang GL, et al. Late course accelerated hyperfractionation radiotherapy plus concurrent chemotherapy for squamous cell carcinoma of the esophagus: a phase III randomized study. Int J Radiat Oncol Biol Phys. 2005;62:1014–1020
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  17. Cassidy J, Clarke S, Díaz-Rubio E, et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol. 2008;26:2006–2012
  18. Souglakos J, Androulakis N, Kakolyris S, et al. Multicenter dose-finding study of concurrent capecitabine and radiotherapy as adjuvant treatment for operative rectal cancer. Int J Radiat Oncol Biol Phys. 2003;56:1284–1287
  19. Czito BG, Kelsey CR, Hurwitz HI, et al. A Phase I study of capecitabine, carboplatin, and paclitaxel with external beam radiation therapy for esophageal carcinoma. Int J Radiat Oncol Biol Phys. 2007;67:1002–1007

PII: S0167-8140(09)00435-6

doi: 10.1016/j.radonc.2009.08.002

Radiotherapy & Oncology
Volume 93, Issue 3 , Pages 458-461 , December 2009

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