Radiotherapy & Oncology
Volume 93, Issue 3 , Pages 534-538 , December 2009

Erosive potential of saliva stimulating tablets with and without fluoride in irradiated head and neck cancer patients

  • Christel Lajer

      Affiliations

    • Department of Otolaryngology Head and Neck Surgery, Rigshospitalet, University of Copenhagen, Denmark
    • Corresponding Author InformationCorresponding author. Address: Department of Otolaryngology Head and Neck Surgery, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark.
    • ,
  • Christian Buchwald

      Affiliations

    • Department of Otolaryngology Head and Neck Surgery, Rigshospitalet, University of Copenhagen, Denmark
    • ,
  • Birgitte Nauntofte

      Affiliations

    • Department of Oral Medicine, Faculty of Health Science, University of Copenhagen, Denmark
    • ,
  • Lena Specht

      Affiliations

    • Department of Oncology, Rigshospitalet, University of Copenhagen, Denmark
    • ,
  • Allan Bardow

      Affiliations

    • Department of Oral Medicine, Faculty of Health Science, University of Copenhagen, Denmark
    • ,
  • Thorbjörg Jensdottir

      Affiliations

    • Department of Oral Medicine, Faculty of Health Science, University of Copenhagen, Denmark

Received 6 February 2009 ,Revised 8 June 2009 ,Accepted 27 June 2009.

References 

  1. Leone CW, Oppenheim FG. Physical and chemical aspects of saliva as indicators of risk for dental caries in humans. J Dent Educ. 2001;65:1054–1062
  2. Jarvinen VK, Rytomaa II, Heinonen OP. Risk factors in dental erosion. J Dent Res. 1991;70:942–947
  3. Jensen SB, Pedersen AM, Reibel J, Nauntofte B. Xerostomia and hypofunction of the salivary glands in cancer therapy. Support Care Cancer. 2003;11:207–225
  4. Jensdottir T, Nauntofte B, Buchwald C, Hansen HS, Bardow A. Effects of sucking acidic candies on saliva in unilaterally irradiated pharyngeal cancer patients. Oral Oncol. 2006;42:317–322
  5. Chao KS, Deasy JO, Markman J, Haynie J, Perez CA, Purdy JA, et al. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys. 2001;49:907–916
  6. Chambers MS, Garden AS, Kies MS, Martin JW. Radiation-induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management. Head Neck. 2004;26:796–807
  7. Spielman AI. Interaction of saliva and taste. J Dent Res. 1990;69:838–843
  8. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341–1346
  9. Bardow A, Moe D, Nyvad B, Nauntofte B. The buffer capacity and buffer systems of human whole saliva measured without loss of CO2. Arch Oral Biol. 2000;45:1–12
  10. Navazesh M, Christensen CM. A comparison of whole mouth resting and stimulated salivary measurement procedures. J Dent Res. 1982;61:1158–1162
  11. Patel PR, Brown WE. Thermodynamic solubility product of human tooth enamel: powdered sample. J Dent Res. 1975;54:728–736
  12. Jensdottir T, Nauntofte B, Buchwald C, Bardow A. Effects of sucking acidic candy on whole-mouth saliva composition. Caries Res. 2005;39:468–474
  13. Larsen MJ, Pearce EI. Saturation of human saliva with respect to calcium salts. Arch Oral Biol. 2003;48:317–322
  14. Guggenheimer J, Moore PA. Xerostomia: etiology, recognition and treatment. J Am Dent Assoc. 2003;134:61–69
  15. Garcia-Godoy F, Hicks MJ. Maintaining the integrity of the enamel surface: the role of dental biofilm, saliva and preventive agents in enamel demineralization and remineralization. J Am Dent Assoc. 2008;139:25S–34S
  16. Scrimger R, Kanji A, Parliament M, Warkentin H, Field C, Jha N, et al. Correlation between saliva production and quality of life measurements in head and neck cancer patients treated with intensity-modulated radiotherapy. Am J Clin Oncol. 2007;30:271–277
  17. Dawes C. The effects of flow rate and duration of stimulation on the concentrations of protein and the main electrolytes in human parotid saliva. Arch Oral Biol. 1969;14:277–294
  18. Jensdottir T, Nauntofte B, Buchwald C, Bardow A. Effects of calcium on the erosive potential of acidic candies in saliva. Caries Res. 2007;41:68–73

PII: S0167-8140(09)00342-9

doi: 10.1016/j.radonc.2009.06.028

Radiotherapy & Oncology
Volume 93, Issue 3 , Pages 534-538 , December 2009

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