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Radiotherapy & Oncology
Volume 91, Issue 1
, Pages 16-22
, April 2009
Accelerated partial breast irradiation trials: Diversity in rationale and design
References
- . Accelerated partial breast irradiation as part of breast conserving therapy of early breast carcinoma: a systematic review. Radiother Oncol. 2009;90:1–13
- Intraoperative radiation therapy with electrons (ELIOT) in early-stage breast cancer. Breast. 2003;12:483–490
- Vaidya JS, Baum M, Tobias JS, Houghton J. Lancet. Targeted intraoperative radiotherapy; 1999. Available from: http://www.thelancet.com/journals/lancet/misc/protocol/99PRT-47.
- Strnad V, Polgar C. On behalf of the European Brachytherapy Breast Cancer GEC-ESTRO Working Group. GEC-ESTRO APBI Trial: Interstitial brachytherapy alone versus external beam radiation therapy after breast conserving surgery for low risk invasive carcinoma and low risk duct carcinoma in-situ (DCIS) of the female breast; 2006. Available from: http://www.apbi.uni-erlangen.de/outline/outline.html.
- Wolmark N, Curran WJ. On behalf of NSABP and RTOG of the American College of Radiology (ACR). NSABP Protocol B-39. RTOG Protocol 0413. A randomized phase III study of conventional whole breast irradiation versus partial breast irradiation for women with stage 0, I, or II breast cancer. National surgical adjuvant breast and bowel project (NSABP). Trial protocol March 13, 2007. p. 1–132.
- OCOG. Ontario Clinical Oncology Group (OCOG), Canadian Institutes of Health Research (CIHR), Canadian Breast Cancer Research Alliance. RAPID: Randomized Trial of Accelerated Partial Breast Irradiation; 2008. Available from: http://clinicaltrials.gov/ct2/show/NCT00282035.
- Yarnold J, Coles C. On behalf of the IMPORT LOW Trial Management Group: Intensity Modulated and Partial Organ Radiotherapy. Randomised trial testing intensity modulated and partial organ radiotherapy following breast conservation surgery for early breast cancer. Trial Protocol, version 4. Sutton, Surrey, UK: The Institute of Cancer Research, Royal Cancer Hospital; 2008. p. 1–74.
- TARGeted Intraoperative radiotherapy (TARGIT): an innovative approach to partial-breast irradiation. Semin Radiat Oncol. 2005;15:84–91
- Radiotherapy after breast-conserving surgery in small breast carcinoma: long-term results of a randomized trial. Ann Oncol. 2001;12:997–1003
- Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347:1227–1232
- Vaidya JS. A novel approach for local treatment of breast cancer. University of London; 2001. p. 236. Available from: http://www.personal.dundee.ac.uk/jsvaidya/papers/cvjsv.htm.
- . Multicentricity of breast cancer: whole-organ analysis and clinical implications. Br J Cancer. 1996;74:820–824
- . Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science. 1996;274:2057–2059
- A preliminary report of intraoperative radiotherapy (IORT) in limited-stage breast cancers that are conservatively treated. Eur J Cancer. 2001;37:2178–2183
- . Clinical relative biological effectiveness of low-energy X-rays emitted by miniature X-ray devices. Phys Med Biol. 1999;44:323–333
- Interstitial brachytherapy alone after breast conserving surgery: interim results of a German-Austrian multicenter phase II trial. Brachytherapy. 2004;3:115–119
- Sole brachytherapy of the tumor bed after conservative surgery for T1 breast cancer: five-year results of a phase I–II study and initial findings of a randomized phase III trial. J Surg Oncol. 2002;80:121–128discussion 129
- . Defining the clinical target volume for patients with early-stage breast cancer treated with lumpectomy and accelerated partial breast irradiation: a pathologic analysis. Int J Radiat Oncol Biol Phys. 2004;60:722–730
- Initial clinical experience with the MammoSite breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2003;55:289–293
- Ongoing clinical experience utilizing 3D conformal external beam radiotherapy to deliver partial-breast irradiation in patients with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2003;57:1247–1253
- Available from: http://groups.eortc.be/radio/res/irma/synopsis_trial_irma1.pdf.
- . The IMPORT trials are launched (September 2006). Clin Oncol (R Coll Radiol). 2006;18:587–590
- . Time factor and treatment strategies in subclinical disease. Int J Radiat Biol. 2003;79:495–502
- The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet Oncol. 2008;9:331–341
- . Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6). II. Relation of local breast recurrence to multicentricity. Cancer. 1986;57:1717–1724
- 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial. J Clin Oncol. 1999;17:2326–2333
- Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group. J Natl Cancer Inst. 1996;88:1659–1664
- Breast conservation surgery, with and without radiotherapy, in women with lymph node-negative breast cancer: a randomised clinical trial in a population with access to public mammography screening. Eur J Cancer. 2003;39:1690–1697
- Local recurrence after breast-conserving surgery and radiotherapy. Frequency, time course, and prognosis. Cancer. 1989;63:1912–1917
- Time-course of local recurrence following conservative surgery and radiotherapy for early stage breast cancer. Int J Radiat Oncol Biol Phys. 1988;15:255–261
- Local recurrences and distant metastases after conservative breast cancer treatments: partly independent events. J Natl Cancer Inst. 1995;87:19–27
- . True recurrence vs. new primary ipsilateral breast tumor relapse: an analysis of clinical and pathologic differences and their implications in natural history, prognoses, and therapeutic management. Int J Radiat Oncol Biol Phys. 2000;48:1281–1289
- Classifying local disease recurrences after breast conservation therapy based on location and histology: new primary tumors have more favorable outcomes than true local disease recurrences. Cancer. 2002;95:2059–2067
- . Pattern of local recurrence after conservative surgery and whole-breast irradiation. Int J Radiat Oncol Biol Phys. 2005;61:1328–1336
- . Changes in temporal patterns of local failure after breast-conserving therapy and their prognostic implications. Int J Radiat Oncol Biol Phys. 2004;60:731–740
- Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-year results of the randomized boost versus no boost EORTC 22881-10882 trial. J Clin Oncol. 2007;25:3259–3265
- . Histologic multifocality of Tis, T1-2 breast carcinomas. Implications for clinical trials of breast-conserving surgery. Cancer. 1985;56:979–990
- . Monomorphic epithelial proliferations: characterization and evidence suggesting they are the pool of partially transformed lesions from which some invasive carcinomas arise. Am J Clin Pathol. 2007;128:1023–1034
- . Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients. Cancer Res. 2002;62:1000–1003
- Genetic alterations in ‘normal’ luminal and myoepithelial cells of the breast. J Pathol. 1999;189:496–503
- . Breast recurrence following conservative surgery and radiation: patterns of failure, prognosis, and pathologic findings from mastectomy specimens with implications for treatment. Int J Radiat Oncol Biol Phys. 1990;19:833–842
- Analysis of ipsilateral breast tumor recurrences after breast-conserving treatment based on the classification of true recurrences and new primary tumors. Breast Cancer. 2005;12:104–111
- . Escaping from Flatland: clinical and biological aspects of human mammary duct anatomy in three dimensions. J Pathol. 2004;203:538–544
- Intraductal extension of primary invasive breast carcinoma treated by breast-conservative surgery. Computer graphic three-dimensional reconstruction of the mammary duct-lobular systems. Cancer. 1995;76:32–45
- . Breast-duct endoscopy to study stages of cancerous breast disease. Lancet. 1996;348:997–999
- . Routine operative breast endoscopy during lumpectomy. Ann Surg Oncol. 2003;10:38–42
- . Multicentric mammary carcinoma: evidence of monoclonal proliferation. Cancer. 2002;94:1910–1916
- The use of molecular assays to establish definitively the clonality of ipsilateral breast tumor recurrences and patterns of in-breast failure in patients with early-stage breast cancer treated with breast-conserving therapy. Cancer. 2007;109:1264–1272
- Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233–1241
- Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial. Scottish Cancer Trials Breast Group. Lancet. 1996;348:708–713
- Tamoxifen, radiation therapy, or both for prevention of ipsilateral breast tumor recurrence after lumpectomy in women with invasive breast cancers of one centimeter or less. J Clin Oncol. 2002;20:4141–4149
- Radiation therapy after breast-conserving surgery; first results of a randomised clinical trial in patients with low risk of recurrence. Eur J Cancer. 2004;40:998–1005
- Lumpectomy plus tamoxifen or anastrozole with or without whole breast irradiation in women with favorable early breast cancer. Int J Radiat Oncol Biol Phys. 2007;68:334–340
- Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366:2087–2106
- . Local relapse rates are falling after breast conserving surgery and systemic therapy for early breast cancer: can radiotherapy ever be safely withheld?. Radiother Oncol. 2009;90:14–22
- Dr. Boon Chua, Personal Communication.
PII: S0167-8140(08)00681-6
doi: 10.1016/j.radonc.2008.12.011
© 2009 Elsevier Ireland Ltd. All rights reserved.
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Radiotherapy & Oncology
Volume 91, Issue 1
, Pages 16-22
, April 2009
