Radiotherapy & Oncology
Volume 88, Issue 3 , Pages 326-334 , September 2008

Transition from a simple to a more advanced dose calculation algorithm for radiotherapy of non-small cell lung cancer (NSCLC): Implications for clinical implementation in an individualized dose-escalation protocol

Received 11 March 2008 ,Revised 26 June 2008 ,Accepted 6 July 2008.

References 

  1. Papanikolaou N, Battista J, Boyer A, et al. AAPM report no 85, Tissue inhomogeneity corrections for megavoltage photon beams. Madison (WI): Medical Physics Publishing; 2004.
  2. Haedinger U, Krieger T, Flentje M, Wulf J. Influence of calculation model on dose distribution in stereotactic radiotherapy for pulmonary targets. Int J Radiat Oncol Biol Phys. 2005;61:239–249
  3. Engelsman M, Damen EM, Koken PW, van’t Veld AA, van Ingen KM, Mijnheer BJ. Impact of simple tissue inhomogeneity correction algorithms on conformal radiotherapy of lung tumours. Radiother Oncol. 2001;60:299–309
  4. De Jaeger K, Hoogeman MS, Engelsman M, et al. Incorporating an improved dose-calculation algorithm in conformal radiotherapy of lung cancer: re-evaluation of dose in normal lung tissue. Radiother Oncol. 2003;69:1–10
  5. Bragg CM, Wingate K, Conway J. Clinical implications of the anisotropic analytical algorithm for IMRT treatment planning and verification. Radiother Oncol. 2008;86:276–284
  6. Morgan AM, Knoos T, McNee SG, Evans CJ, Thwaites DI. Clinical implications of the implementation of advanced treatment planning algorithms for thoracic treatments. Radiother Oncol. 2008;86:48–54
  7. Fogliata A, Vanetti E, Albers D, et al. On the dosimetric behaviour of photon dose calculation algorithms in the presence of simple geometric heterogeneities: comparison with Monte Carlo calculations. Phys Med Biol. 2007;52:1363–1385
  8. Knöös T, Wieslander E, Cozzi L, et al. Comparison of dose calculation algorithms for treatment planning in external photon beam therapy for clinical situations. Phys Med Biol. 2006;51:5785–5807
  9. Garcia-Vicente F, Minambres A, Jerez I, Modolell I, Perez L, Torres JJ. Experimental validation tests of fast Fourier transform convolution and multigrid superposition algorithms for dose calculation in low-density media. Radiother Oncol. 2003;67:239–249
  10. van Elmpt WJ, Nijsten SM, Dekker AL, Mijnheer BJ, Lambin P. Treatment verification in the presence of inhomogeneities using EPID-based three-dimensional dose reconstruction. Med Phys. 2007;34:2816–2826
  11. Scholz C, Schulze C, Oelfke U, Bortfeld T. Development and clinical application of a fast superposition algorithm in radiation therapy. Radiother Oncol. 2003;69:79–90
  12. ICRU. International Commission on Radiation Units and Measurements Report 50: Prescribing, recording, and reporting photon beam therapy: Bethesda. 1993.
  13. Belderbos JS, Heemsbergen WD, De Jaeger K, Baas P, Lebesque JV. Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys. 2006;66:126–134
  14. Bradley J, Graham MV, Winter K, et al. Toxicity and outcome results of RTOG 9311: a phase I–II dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma. Int J Radiat Oncol Biol Phys. 2005;61:318–328
  15. Hayman JA, Martel MK, Ten Haken RK, et al. Dose escalation in non-small-cell lung cancer using three-dimensional conformal radiation therapy: update of a phase I trial. J Clin Oncol. 2001;19:127–136
  16. Kong FM, Ten Haken RK, Schipper MJ, et al. High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non-small-cell lung cancer: long-term results of a radiation dose escalation study. Int J Radiat Oncol Biol Phys. 2005;63:324–333
  17. Mehta M, Scrimger R, Mackie R, Paliwal B, Chappell R, Fowler J. A new approach to dose escalation in non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2001;49:23–33
  18. Kong FM, Hayman JA, Griffith KA, et al. Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): predictors for radiation pneumonitis and fibrosis. Int J Radiat Oncol Biol Phys. 2006;65:1075–1086
  19. Yorke ED, Jackson A, Rosenzweig KE, Braban L, Leibel SA, Ling CC. Correlation of dosimetric factors and radiation pneumonitis for non-small-cell lung cancer patients in a recently completed dose escalation study. Int J Radiat Oncol Biol Phys. 2005;63:672–682
  20. Miften M, Wiesmeyer M, Monthofer S, Krippner K. Implementation of FFT convolution and multigrid superposition models in the FOCUS RTP system. Phys Med Biol. 2000;45:817–833
  21. Kwa SL, Lebesque JV, Theuws JC, et al. Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys. 1998;42:1–9
  22. van Baardwijk A, Bosmans G, Boersma L, et al. Individualized radical radiotherapy of non-small-cell lung cancer based on normal tissue dose constraints: a feasibility study. Int J Radiat Oncol Biol Phys. 2008;71:1394–1401
  23. Marks LB, Garst J, Socinski MA, et al. Carboplatin/paclitaxel or carboplatin/vinorelbine followed by accelerated hyperfractionated conformal radiation therapy: report of a prospective phase I dose escalation trial from the Carolina Conformal Therapy Consortium. J Clin Oncol. 2004;22:4329–4340
  24. Engelsman M, Remeijer P, van Herk M, Lebesque JV, Mijnheer BJ, Damen EM. Field size reduction enables iso-NTCP escalation of tumor control probability for irradiation of lung tumors. Int J Radiat Oncol Biol Phys. 2001;51:1290–1298
  25. Niemierko A. Reporting and analyzing dose distributions: a concept of equivalent uniform dose. Med Phys. 1997;24:103–110
  26. van Elmpt WJ, Nijsten SM, Schiffeleers RF, et al. A Monte Carlo based three-dimensional dose reconstruction method derived from portal dose images. Med Phys. 2006;33:2426–2434
  27. van Elmpt W, Nijsten S, Mijnheer B, Dekker A, Lambin P. The next step in patient-specific QA: 3D dose verification of conformal and intensity-modulated RT based on EPID dosimetry and Monte Carlo dose calculations. Radiother Oncol. 2008;86:86–92
  28. Irvine C, Morgan A, Crellin A, Nisbet A, Beange I. The clinical implications of the collapsed cone planning algorithm. Clin Oncol (R Coll Radiol). 2004;16:148–154
  29. Webb S, Nahum AE. A model for calculating tumour control probability in radiotherapy including the effects of inhomogeneous distributions of dose and clonogenic cell density. Phys Med Biol. 1993;38:653–666
  30. Schwarz M, Alber M, Lebesque JV, Mijnheer BJ, Damen EM. Dose heterogeneity in the target volume and intensity-modulated radiotherapy to escalate the dose in the treatment of non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2005;62:561–570
  31. Fowler JF, Tome WA, Fenwick JD, Mehta MP. A challenge to traditional radiation oncology. Int J Radiat Oncol Biol Phys. 2004;60:1241–1256

PII: S0167-8140(08)00366-6

doi: 10.1016/j.radonc.2008.07.003

Radiotherapy & Oncology
Volume 88, Issue 3 , Pages 326-334 , September 2008