Radiotherapy & Oncology
Volume 87, Issue 3 , Pages 339-342, June 2008

Contrast enhanced 4D-CT imaging for target volume definition in pancreatic ductal adenocarcinoma

  • Pietro Mancosu

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
    • Corresponding Author InformationCorresponding author. Pietro Mancosu, Scientific institute H San. Raffaele, Via Olgettina 60, 20132 Milano, Italy.
  • ,
  • Valentino Bettinardi

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
  • ,
  • Paolo Passoni

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
  • ,
  • Simone Gusmini

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
    • Vita-Salute University, Milano, Italy
  • ,
  • Stefano Cappio

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
    • Vita-Salute University, Milano, Italy
  • ,
  • Maria C. Gilardi

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
    • IBFM-CNR, Institute for Molecular Bioimaging and Physiology, Milano, Italy
    • School of Medicine, University of Milano Bicocca, Milan, Italy
  • ,
  • Giovanni M. Cattaneo

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
  • ,
  • Michele Reni

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
  • ,
  • Alessandro Del Maschio

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
    • Vita-Salute University, Milano, Italy
  • ,
  • Nadia Di Muzio

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
  • ,
  • Ferruccio Fazio

      Affiliations

    • Scientific institute H San. Raffaele, Milano, Italy
    • IBFM-CNR, Institute for Molecular Bioimaging and Physiology, Milano, Italy
    • School of Medicine, University of Milano Bicocca, Milan, Italy

Received 8 February 2008; received in revised form 8 April 2008; accepted 19 April 2008. published online 20 May 2008.

Abstract 

A procedure to improve target volume definition in pancreatic ductal adenocarcinoma by contrast enhanced 4D-CT imaging has been implemented for radiotherapy planning. The procedure allows good quality images to be obtained over the whole patient’s breathing cycle in terms of anatomical details, pancreatic enhancement and vessel definition.

Keywords: Respiratory gated 4D-CT, Contrast medium injection, Pancreatic ductal adenocarcinoma, Radiotherapy

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PII: S0167-8140(08)00228-4

doi:10.1016/j.radonc.2008.04.007

Radiotherapy & Oncology
Volume 87, Issue 3 , Pages 339-342, June 2008