Reirradiation, surgery and IORT for recurrent rectal cancer in previously irradiated patients

Vermaas, Maarten; Nuyttens, Joost J.M.E.; Ferenschild, Floris T.J.; Verhoef, Cornelis; Eggermont, Alexander M.M.; de Wilt, Johannes H.W.

doi:10.1016/j.radonc.2008.02.021

« Previous Next »Radiotherapy & Oncology
Volume 87, Issue 3 , Pages 357-360, June 2008

Reirradiation, surgery and IORT for recurrent rectal cancer in previously irradiated patients

Maarten Vermaas
- Department of Surgical Oncology, andErasmus MC -- Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
Joost J.M.E. Nuyttens
- Department of Radiotherapy, Erasmus MC – Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
Floris T.J. Ferenschild
- Department of Surgical Oncology, andErasmus MC -- Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
Cornelis Verhoef
- Department of Surgical Oncology, andErasmus MC -- Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
Alexander M.M. Eggermont
- Department of Surgical Oncology, andErasmus MC -- Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
Johannes H.W. de Wilt
- Department of Surgical Oncology, andErasmus MC -- Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands
- Corresponding author. Johannes H.W. de Wilt, Department of Surgical Oncology, Erasmus MC – Daniel den Hoed Cancer Centre, P.O. Box 5201, 3008 AE Rotterdam, The Netherlands.

Received 5 November 2007; received in revised form 21 February 2008; accepted 25 February 2008. published online 19 March 2008.

Abstract

A total of 11 patients with recurrent rectal cancer who had been previously irradiated were treated with preoperative reirradiation (median dose 30Gy), surgery and IORT. This treatment was related with high morbidity, a short pain-free survival (5 months) and poor local control (27% after 3 years), although some patients have long-term distant control and survival.